Matrix Metalloproteinases Are Not Essential for Aggrecan Turnover during Normal Skeletal Growth and Development

The growth plate is a transitional region of cartilage and highly diversified chondrocytes that controls long bone formation. The composition of growth plate cartilage changes markedly from the epiphysis to the metaphysis, notably with the loss of type II collagen, concomitant with an increase in MM...

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Autores principales: Little, Christopher B., Meeker, Clare T., Hembry, Rosalind M., Sims, Natalie A., Lawlor, Kate E., Golub, Sue B., Last, Karena, Fosang, Amanda J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1069612/
https://ncbi.nlm.nih.gov/pubmed/15798221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.8.3388-3399.2005
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