The Epstein–Barr virus lytic cycle activator Zta interacts with methylated ZRE in the promoter of host target gene egr1

Por Heather, James, Flower, Kirsty, Isaac, Samine, Sinclair, Alison J.
Publicado em 2009

Dynamic Chromatin Environment of Key Lytic Cycle Regulatory Regions of the Epstein-Barr Virus Genome

Por Ramasubramanyan, Sharada, Osborn, Kay, Flower, Kirsty, Sinclair, Alison J.
Publicado em 2012

Evaluation of a Prediction Protocol to Identify Potential Targets of Epigenetic Reprogramming by the Cancer Associated Epstein Barr Virus

Por Flower, Kirsty, Hellen, Elizabeth, Newport, Melanie J., Jones, Susan, Sinclair, Alison J.
Publicado em 2010

Epigenetic Control of Viral Life-Cycle by a DNA-Methylation Dependent Transcription Factor

Por Flower, Kirsty, Thomas, David, Heather, James, Ramasubramanyan, Sharada, Jones, Susan, Sinclair, Alison J.
Publicado em 2011

Genome-Wide Analyses of Zta Binding to the Epstein-Barr Virus Genome Reveals Interactions in both Early and Late Lytic Cycles and an Epigenetic Switch Leading to an Altered Binding...

Por Ramasubramanyan, Sharada, Kanhere, Aditi, Osborn, Kay, Flower, Kirsty, Jenner, Richard G., Sinclair, Alison J.
Publicado em 2012

Acceleration in the DNA methylation age in breast cancer tumours from very young women

Por Oltra, Sara S., Peña-Chilet, Maria, Flower, Kirsty, Martinez, María Teresa, Alonso, Elisa, Burgues, Octavio, Lluch, Ana, Flanagan, James M., Ribas, Gloria
Publicado no Sci Rep (2019)

Atypical bZIP Domain of Viral Transcription Factor Contributes to Stability of Dimer Formation and Transcriptional Function

Por Schelcher, Celine, Al Mehairi, Salama, Verrall, Elizabeth, Hope, Questa, Flower, Kirsty, Bromley, Beth, Woolfson, Derek N., West, Michelle J., Sinclair, Alison J.
Publicado em 2007

Transcriptional implications of intragenic DNA methylation in the oestrogen receptor alpha gene in breast cancer cells and tissues

Por Shenker, Natalie S, Flower, Kirsty J, Wilhelm-Benartzi, Charlotte S, Dai, Wei, Bell, Emma, Gore, Edmund, El Bahrawy, Mona, Weaver, Gillian, Brown, Robert, Flanagan, James M
Publicado no BMC Cancer (2015)

DNA methylation profiling to assess pathogenicity of BRCA1 unclassified variants in breast cancer

Por Flower, Kirsty J, Shenker, Natalie S, El-Bahrawy, Mona, Goldgar, David E, Parsons, Michael T, Spurdle, Amanda B, Morris, Joanna R, Brown, Robert, Flanagan, James M
Publicado no Epigenetics (2016)

Methylation deregulation of miRNA promoters identifies miR124-2 as a survival biomarker in Breast Cancer in very young women

Por Oltra, Sara S., Peña-Chilet, Maria, Vidal-Tomas, Victoria, Flower, Kirsty, Martinez, María Teresa, Alonso, Elisa, Burgues, Octavio, Lluch, Ana, Flanagan, James M., Ribas, Gloria
Publicado no Sci Rep (2018)

Stilbenoids remodel the DNA methylation patterns in breast cancer cells and inhibit oncogenic NOTCH signaling through epigenetic regulation of MAML2 transcriptional activity

Por Lubecka, Katarzyna, Kurzava, Lucinda, Flower, Kirsty, Buvala, Hannah, Zhang, Hao, Teegarden, Dorothy, Camarillo, Ignacio, Suderman, Matthew, Kuang, Shihuan, Andrisani, Ourania, Flanagan, James M., Stefanska, Barbara
Publicado no Carcinogenesis (2016)

Loci-specific differences in blood DNA methylation in HBV-negative populations at risk for hepatocellular carcinoma development

Por Lubecka, Katarzyna, Flower, Kirsty, Beetch, Megan, Qiu, Jay, Kurzava, Lucinda, Buvala, Hannah, Ruhayel, Adam, Gawrieh, Samer, Liangpunsakul, Suthat, Gonzalez, Tracy, McCabe, George, Chalasani, Naga, Flanagan, James M, Stefanska, Barbara
Publicado no Epigenetics (2018)

Methylation of MYLK3 gene promoter region: a biomarker to stratify surgical care in ovarian cancer in a multicentre study

Por Phelps, David L, Borley, Jane V, Flower, Kirsty J, Dina, Roberto, Darb-Esfahani, Silvia, Braicu, Ioana, Sehouli, Jalid, Fotopoulou, Christina, Wilhelm-Benartzi, Charlotte S, Gabra, Hani, Yazbek, Joseph, Chatterjee, Jayanta, Ip, Jacey, Khan, Harun, Likos-Corbett, Marina-Therese, Brown, Robert, Ghaem-Maghami, Sadaf
Publicado no Br J Cancer (2017)

Epigenome-wide association study reveals decreased average methylation levels years before breast cancer diagnosis

Por van Veldhoven, Karin, Polidoro, Silvia, Baglietto, Laura, Severi, Gianluca, Sacerdote, Carlotta, Panico, Salvatore, Mattiello, Amalia, Palli, Domenico, Masala, Giovanna, Krogh, Vittorio, Agnoli, Claudia, Tumino, Rosario, Frasca, Graziella, Flower, Kirsty, Curry, Ed, Orr, Nicholas, Tomczyk, Katarzyna, Jones, Michael E., Ashworth, Alan, Swerdlow, Anthony, Chadeau-Hyam, Marc, Lund, Eiliv, Garcia-Closas, Montserrat, Sandanger, Torkjel M., Flanagan, James M., Vineis, Paolo
Publicado no Clin Epigenetics (2015)