Atypical bZIP Domain of Viral Transcription Factor Contributes to Stability of Dimer Formation and Transcriptional Function

The Epstein-Barr virus transcription factor Zta (encoded by BZLF1) is a bZIP protein containing an α-helical coiled-coil homodimerization motif (zipper). The Zta zipper forms less-stable dimers than other bZIP proteins, and an adjacent region (CT) interacts with the zipper to form a novel structure...

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Detalhes bibliográficos
Main Authors: Schelcher, Celine, Al Mehairi, Salama, Verrall, Elizabeth, Hope, Questa, Flower, Kirsty, Bromley, Beth, Woolfson, Derek N., West, Michelle J., Sinclair, Alison J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933325/
https://ncbi.nlm.nih.gov/pubmed/17459922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00215-07
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