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Methylation deregulation of miRNA promoters identifies miR124-2 as a survival biomarker in Breast Cancer in very young women

MiRNAs are part of the epigenetic machinery, and are also epigenetically modified by DNA methylation. MiRNAs regulate expression of different genes, so any alteration in their methylation status may affect their expression. We aimed to identify methylation differences in miRNA encoding genes in brea...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Oltra, Sara S., Peña-Chilet, Maria, Vidal-Tomas, Victoria, Flower, Kirsty, Martinez, María Teresa, Alonso, Elisa, Burgues, Octavio, Lluch, Ana, Flanagan, James M., Ribas, Gloria
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158237/
https://ncbi.nlm.nih.gov/pubmed/30258192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32393-3
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