Methylation deregulation of miRNA promoters identifies miR124-2 as a survival biomarker in Breast Cancer in very young women

MiRNAs are part of the epigenetic machinery, and are also epigenetically modified by DNA methylation. MiRNAs regulate expression of different genes, so any alteration in their methylation status may affect their expression. We aimed to identify methylation differences in miRNA encoding genes in brea...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Oltra, Sara S., Peña-Chilet, Maria, Vidal-Tomas, Victoria, Flower, Kirsty, Martinez, María Teresa, Alonso, Elisa, Burgues, Octavio, Lluch, Ana, Flanagan, James M., Ribas, Gloria
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158237/
https://ncbi.nlm.nih.gov/pubmed/30258192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32393-3
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