Transcriptional implications of intragenic DNA methylation in the oestrogen receptor alpha gene in breast cancer cells and tissues

BACKGROUND: DNA methylation variability regions (MVRs) across the oestrogen receptor alpha (ESR1) gene have been identified in peripheral blood cells from breast cancer patients and healthy individuals. In contrast to promoter methylation, gene body methylation may be important in maintaining active...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Shenker, Natalie S, Flower, Kirsty J, Wilhelm-Benartzi, Charlotte S, Dai, Wei, Bell, Emma, Gore, Edmund, El Bahrawy, Mona, Weaver, Gillian, Brown, Robert, Flanagan, James M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424887/
https://ncbi.nlm.nih.gov/pubmed/25927974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1335-5
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