Epigenome-wide association study reveals decreased average methylation levels years before breast cancer diagnosis

BACKGROUND: Interest in the potential of DNA methylation in peripheral blood as a biomarker of cancer risk is increasing. We aimed to assess whether epigenome-wide DNA methylation measured in peripheral blood samples obtained before onset of the disease is associated with increased risk of breast ca...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: van Veldhoven, Karin, Polidoro, Silvia, Baglietto, Laura, Severi, Gianluca, Sacerdote, Carlotta, Panico, Salvatore, Mattiello, Amalia, Palli, Domenico, Masala, Giovanna, Krogh, Vittorio, Agnoli, Claudia, Tumino, Rosario, Frasca, Graziella, Flower, Kirsty, Curry, Ed, Orr, Nicholas, Tomczyk, Katarzyna, Jones, Michael E., Ashworth, Alan, Swerdlow, Anthony, Chadeau-Hyam, Marc, Lund, Eiliv, Garcia-Closas, Montserrat, Sandanger, Torkjel M., Flanagan, James M., Vineis, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524428/
https://ncbi.nlm.nih.gov/pubmed/26244061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0104-2
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