Epigenome-wide association study reveals decreased average methylation levels years before breast cancer diagnosis

BACKGROUND: Interest in the potential of DNA methylation in peripheral blood as a biomarker of cancer risk is increasing. We aimed to assess whether epigenome-wide DNA methylation measured in peripheral blood samples obtained before onset of the disease is associated with increased risk of breast ca...

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Bibliografiske detaljer
Udgivet i:Clin Epigenetics
Main Authors: van Veldhoven, Karin, Polidoro, Silvia, Baglietto, Laura, Severi, Gianluca, Sacerdote, Carlotta, Panico, Salvatore, Mattiello, Amalia, Palli, Domenico, Masala, Giovanna, Krogh, Vittorio, Agnoli, Claudia, Tumino, Rosario, Frasca, Graziella, Flower, Kirsty, Curry, Ed, Orr, Nicholas, Tomczyk, Katarzyna, Jones, Michael E., Ashworth, Alan, Swerdlow, Anthony, Chadeau-Hyam, Marc, Lund, Eiliv, Garcia-Closas, Montserrat, Sandanger, Torkjel M., Flanagan, James M., Vineis, Paolo
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524428/
https://ncbi.nlm.nih.gov/pubmed/26244061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0104-2
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