Epigenome-wide association study reveals decreased average methylation levels years before breast cancer diagnosis

BACKGROUND: Interest in the potential of DNA methylation in peripheral blood as a biomarker of cancer risk is increasing. We aimed to assess whether epigenome-wide DNA methylation measured in peripheral blood samples obtained before onset of the disease is associated with increased risk of breast ca...

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Publié dans:Clin Epigenetics
Auteurs principaux: van Veldhoven, Karin, Polidoro, Silvia, Baglietto, Laura, Severi, Gianluca, Sacerdote, Carlotta, Panico, Salvatore, Mattiello, Amalia, Palli, Domenico, Masala, Giovanna, Krogh, Vittorio, Agnoli, Claudia, Tumino, Rosario, Frasca, Graziella, Flower, Kirsty, Curry, Ed, Orr, Nicholas, Tomczyk, Katarzyna, Jones, Michael E., Ashworth, Alan, Swerdlow, Anthony, Chadeau-Hyam, Marc, Lund, Eiliv, Garcia-Closas, Montserrat, Sandanger, Torkjel M., Flanagan, James M., Vineis, Paolo
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524428/
https://ncbi.nlm.nih.gov/pubmed/26244061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0104-2
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