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Methylation of MYLK3 gene promoter region: a biomarker to stratify surgical care in ovarian cancer in a multicentre study

BACKGROUND: Survival benefit from surgical debulking of ovarian cancer (OC) is well established, but some women, despite total macroscopic clearance of disease, still have poor prognosis. We aimed to identify biomarkers to predict benefit from conventional surgery. METHODS: Clinical data from women...

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Dettagli Bibliografici
Pubblicato in:Br J Cancer
Autori principali: Phelps, David L, Borley, Jane V, Flower, Kirsty J, Dina, Roberto, Darb-Esfahani, Silvia, Braicu, Ioana, Sehouli, Jalid, Fotopoulou, Christina, Wilhelm-Benartzi, Charlotte S, Gabra, Hani, Yazbek, Joseph, Chatterjee, Jayanta, Ip, Jacey, Khan, Harun, Likos-Corbett, Marina-Therese, Brown, Robert, Ghaem-Maghami, Sadaf
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482730/
https://ncbi.nlm.nih.gov/pubmed/28350786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.83
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