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Epigenetic regulation of the homeobox gene MSX1 associates with platinum resistant disease in high grade serous epithelial ovarian cancer

PURPOSE: Although High Grade Serous Ovarian Cancer (HGSOC) is frequently chemo-responsive, a proportion of patients do not respond to platinum-based chemotherapy at presentation or have progression-free survival of less than 6 months. Validated predictive biomarkers of lack of response would enable...

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Pubblicato in:Clin Cancer Res
Autori principali: Bonito, Nair A., Borley, Jane, Wilhelm-Benartzi, Charlotte S., Ghaem-Maghami, Sadaf, Brown, Robert
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849558/
https://ncbi.nlm.nih.gov/pubmed/26763252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-1669
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