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Human ovarian cancer intrinsic mechanisms regulate lymphocyte activation in response to immune checkpoint blockade

Immune checkpoint blocking antibodies are currently being tested in ovarian cancer (OC) patients and have shown some responses in early clinical trials. However, it remains unclear how human OC cancer cells regulate lymphocyte activation in response to therapy. In this study, we have established and...

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Bibliographic Details
Published in:Cancer Immunol Immunother
Main Authors: Natoli, Marina, Bonito, Nair, Robinson, James D., Ghaem-Maghami, Sadaf, Mao, Yumeng
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347689/
https://ncbi.nlm.nih.gov/pubmed/32200422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-020-02544-5
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