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Human ovarian cancer intrinsic mechanisms regulate lymphocyte activation in response to immune checkpoint blockade

Immune checkpoint blocking antibodies are currently being tested in ovarian cancer (OC) patients and have shown some responses in early clinical trials. However, it remains unclear how human OC cancer cells regulate lymphocyte activation in response to therapy. In this study, we have established and...

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Опубликовано в: :Cancer Immunol Immunother
Главные авторы: Natoli, Marina, Bonito, Nair, Robinson, James D., Ghaem-Maghami, Sadaf, Mao, Yumeng
Формат: Artigo
Язык:Inglês
Опубликовано: Springer Berlin Heidelberg 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347689/
https://ncbi.nlm.nih.gov/pubmed/32200422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-020-02544-5
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