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Cytotoxic T lymphocyte antigen-4 and immune checkpoint blockade
The relationship between cancer and the immune system is complex and provides unique therapeutic opportunities. Cytotoxic T lymphocyte antigen-4 (CTLA-4) is a regulatory molecule that suppresses T cell effector function following initial activation by costimulatory signals. Fully human monoclonal an...
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| Publicado no: | J Clin Invest |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4588295/ https://ncbi.nlm.nih.gov/pubmed/26325034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80012 |
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