NEDD8 and HDACs: promising cotargets in AML

od Bhalla, Kapil N., Fiskus, Warren
Izdano u Blood (2016)

Targeting cistrome and dysregulated transcriptome of post-MPN sAML

od Verstovsek, Srdan, Fiskus, Warren, Manshouri, Taghi, Bhalla, Kapil N.
Izdano u Oncotarget (2017)

Superior efficacy of co-treatment with dual PI3K/mTOR inhibitor NVP-BEZ235 and pan-histone deacetylase inhibitor against human pancreatic cancer

od Venkannagari, Sreedhar, Fiskus, Warren, Peth, Karissa, Atadja, Peter, Hidalgo, Manuel, Maitra, Anirban, Bhalla, Kapil N.
Izdano 2012

Role of acetylation and extra-cellular location of heat shock protein 90α in tumor cell invasion

od Yang, Yonghua, Rao, Rehka, Shen, Jie, Tang, Yun, Fiskus, Warren, Nechtman, John, Atadja, Peter, Bhalla, Kapil
Izdano 2008

EVI1 dysregulation: impact on biology and therapy of myeloid malignancies

od Birdwell, Christine, Fiskus, Warren, Kadia, Tapan M., DiNardo, Courtney D., Mill, Christopher P., Bhalla, Kapil N.
Izdano u Blood Cancer J (2021)

Acetylated hsp70 and KAP1-mediated Vps34 SUMOylation is required for autophagosome creation in autophagy

od Yang, Yonghua, Fiskus, Warren, Yong, Bao, Atadja, Peter, Takahashi, Yoshinori, Pandita, Tej K., Wang, Hong-Gang, Bhalla, Kapil N.
Izdano 2013

Highly effective combination of LSD1 (KDM1A) antagonist and pan-histone deacetylase inhibitor against human AML cells

od Fiskus, Warren, Sharma, Sunil, Shah, Bhavin, Portier, Bryce P., Devaraj, Santhana G. T., Liu, Ka, Iyer, Swaminathan P., Bearss, David, Bhalla, Kapil N.
Izdano u Leukemia (2014)

HEXIM1 induction is mechanistically involved in mediating anti-AML activity of BET protein bromodomain antagonist

od Devaraj, Santhana G. T., Fiskus, Warren, Shah, Bhavin, Qi, Jun, Sun, Baohua, Iyer, Swaminathan P, Sharma, Sunil, Bradner, James E., Bhalla, Kapil N.
Izdano u Leukemia (2015)

BET protein antagonist JQ1 is synergistically lethal with FLT3 tyrosine kinase inhibitor (TKI) and overcomes resistance to FLT3-TKI in AML cells expressing FLT-ITD

od Fiskus, Warren, Sharma, Sunil, Qi, Jun, Shah, Bhavin, Devaraj, Santhana G. T., Leveque, Christopher, Portier, Bryce P., Iyer, Swaminathan, Bradner, James E., Bhalla, Kapil N.
Izdano 2014

Pre-clinical efficacy of combined therapy with novel β-catenin antagonist BC2059 and histone deacetylase inhibitor against AML cells

od Fiskus, Warren, Sharma, Sunil, Saha, Saikat, Shah, Bhavin, Devaraj, Santhana G. T., Sun, Baohua, Horrigan, Stephen, Leveque, Christopher, Zu, Youli, Iyer, Swaminathan, Bhalla, Kapil N.
Izdano u Leukemia (2014)

Heat shock protein 90 inhibition depletes TrkA levels and signaling in human acute leukemia cells

od Rao, Rekha, Nalluri, Srilatha, Fiskus, Warren, Balusu, Ramesh, Joshi, Atul, Mudunuru, Uma, Buckley, Kathleen M., Robbins, Kelly, Ustun, Celalettin, Reuther, Gary W., Bhalla, Kapil N.
Izdano 2010

Overcoming resistance to histone deacetylase inhibitors in human leukemia with the redox modulating compound β-phenylethyl isothiocyanate

od Hu, Yumin, Lu, Weiqin, Chen, Gang, Zhang, Hui, Jia, Yu, Wei, Yue, Yang, Hui, Zhang, Wan, Fiskus, Warren, Bhalla, Kapil, Keating, Michael, Huang, Peng, Garcia-Manero, Guillermo
Izdano 2010

Superior efficacy of a combined epigenetic therapy against human Mantle Cell Lymphoma (MCL) cells

od Fiskus, Warren, Rao, Rekha, Balusu, Ramesh, Ganguly, Siddhartha, Tao, Jianguo, Sotomayor, Eduardo, Mudunuru, Uma, Smith, Jacqueline E., Hembruff, Stacey L., Atadja, Peter, Marquez, Victor E., Bhalla, Kapil
Izdano 2012

Role of C/EBP homologous protein (CHOP) in Panobinostat-mediated potentiation of Bortezomib-induced lethal ER stress in Mantle Cell Lymphoma cells

od Rao, Rekha, Nalluri, Srilatha, Fiskus, Warren, Savoie, Andrew, Buckley, Kathleen M, Ha, Kyungsoo, Balusu, Ramesh, Joshi, Atul, Coothankandaswamy, Veena, Tao, Jianguo, Sotomayor, Eduardo, Atadja, Peter, Bhalla, Kapil N.
Izdano 2010

miR-137 Targets p160 Steroid Receptor Coactivators SRC1, SRC2, and SRC3 and Inhibits Cell Proliferation

od Eedunuri, Vijay Kumar, Rajapakshe, Kimal, Fiskus, Warren, Geng, Chuandong, Chew, Sue Anne, Foley, Christopher, Shah, Shrijal S., Shou, John, Mohamed, Junaith S., Coarfa, Cristian, O'Malley, Bert W., Mitsiades, Nicholas
Izdano u Mol Endocrinol (2015)

Comprehensive proteomic profiling identifies the androgen receptor axis and other signaling pathways as targets of microRNAs suppressed in metastatic prostate cancer

od Coarfa, Cristian, Fiskus, Warren, Eedunuri, Vijay Kumar, Rajapakshe, Kimal, Foley, Christopher, Chew, Sue Anne, Shah, Shrijal S., Geng, Chuandong, Shou, John, Mohamed, Junaith S., O’Malley, Bert W., Mitsiades, Nicholas
Izdano u Oncogene (2015)

Panobinostat treatment depletes EZH2 and DNMT1 levels and enhances decitabine mediated de-repression of JunB and loss of survival of human acute leukemia cells

od Fiskus, Warren, Buckley, Kate, Rao, Rekha, Mandawat, Aditya, Yang, Yonghua, Joshi, Rajeshree, Wang, Yongchao, Balusu, Ramesh, Chen, Jianguang, Koul, Sanjay, Joshi, Atul, Upadhyay, Sunil, Atadja, Peter, Bhalla, Kapil N.
Izdano 2009

Histone deacetylase inhibitor treatment induces ‘BRCAness’ and synergistic lethality with PARP inhibitor and cisplatin against human triple negative breast cancer cells

od Ha, Kyungsoo, Fiskus, Warren, Choi, Dong Soon, Bhaskara, Srividya, Cerchietti, Leandro, Devaraj, Santhana G. T., Shah, Bhavin, Sharma, Sunil, Chang, Jenny C., Melnick, Ari M., Hiebert, Scott, Bhalla, Kapil N.
Izdano 2014

SIRT2 deacetylates and inhibits the peroxidase activity of peroxiredoxin-1 to sensitize breast cancer cells to oxidant stress inducing agents

od Fiskus, Warren, Coothankandaswamy, Veena, Chen, Jianguang, Ma, Hongwei, Ha, Kyungsoo, Saenz, Dyana T., Krieger, Stephanie S., Mill, Christopher P., Sun, Baohua, Huang, Peng, Mumm, Jeffrey S., Melnick, Ari M., Bhalla, Kapil N.
Izdano u Cancer Res (2016)

Heat shock protein 90 inhibitor is synergistic with JAK2 inhibitor and overcomes resistance to JAK2-TKI in human myeloproliferative neoplasm cells

od Fiskus, Warren, Verstovsek, Srdan, Manshouri, Taghi, Rao, Rekha, Balusu, Ramesh, Venkannagari, Sreedhar, Nalabothula, Narasimha Rao, Ha, Kyungsoo, Smith, Jacqueline E., Hembruff, Stacey, Abhyankar, Sunil, McGuirk, Joseph, Bhalla, Kapil N.
Izdano 2011