Epoxide based inhibitors of the hepatitis C virus non-structural 2 autoprotease

por Shaw, Joseph, Fishwick, Colin W.G., Harris, Mark
Publicado no Antiviral Res (2015)

Identification of a lead like inhibitor of the hepatitis C virus non-structural NS2 autoprotease

por Shaw, Joseph, Harris, Mark, Fishwick, Colin W.G.
Publicado no Antiviral Res (2015)

Linezolid and Tiamulin Cross-Resistance in Staphylococcus aureus Mediated by Point Mutations in the Peptidyl Transferase Center

por Miller, Keith, Dunsmore, Colin J., Fishwick, Colin W. G., Chopra, Ian
Publicado em 2008

Identification of an Indazole-Based Pharmacophore for the Inhibition of FGFR Kinases Using Fragment-Led de Novo Design

por Turner, Lewis D., Summers, Abbey J., Johnson, Laura O., Knowles, Margaret A., Fishwick, Colin W. G.
Publicado no ACS Med Chem Lett (2017)

Selective Phosphonylation of 5′-Adenosine Monophosphate (5′-AMP) via Pyrophosphite [PPi(III)]

por Kaye, Karl, Bryant, David E., Marriott, Katie E. R., Ohara, Shohei, Fishwick, Colin W. G., Kee, Terence P.
Publicado no Orig Life Evol Biosph (2016)

Activity of and Development of Resistance to Corallopyronin A, an Inhibitor of RNA Polymerase

por Mariner, Katherine, McPhillie, Martin, Trowbridge, Rachel, Smith, Catriona, O'Neill, Alex J., Fishwick, Colin W. G., Chopra, Ian
Publicado em 2011

Determinants of Hepatitis C Virus p7 Ion Channel Function and Drug Sensitivity Identified In Vitro

por StGelais, Corine, Foster, Toshana L., Verow, Mark, Atkins, Elizabeth, Fishwick, Colin W. G., Rowlands, David, Harris, Mark, Griffin, Stephen
Publicado em 2009

Furanyl-Rhodanines Are Unattractive Drug Candidates for Development as Inhibitors of Bacterial RNA Polymerase

por Mariner, Katherine R., Trowbridge, Rachel, Agarwal, Anil K., Miller, Keith, O'Neill, Alex J., Fishwick, Colin W. G., Chopra, Ian
Publicado em 2010

Structure-Based Identification and Characterization of Inhibitors of the Epilepsy-Associated K(Na)1.1 (KCNT1) Potassium Channel

por Cole, Bethan A., Johnson, Rachel M., Dejakaisaya, Hattapark, Pilati, Nadia, Fishwick, Colin W.G., Muench, Stephen P., Lippiat, Jonathan D.
Publicado no iScience (2020)

Structure-switching M(3)L(2) Ir(iii) coordination cages with photo-isomerising azo-aromatic linkers

por Oldknow, Samuel, Martir, Diego Rota, Pritchard, Victoria E., Blitz, Mark A., Fishwick, Colin W. G., Zysman-Colman, Eli, Hardie, Michaele J.
Publicado no Chem Sci (2018)

Structure-Based Ligand Design of Novel Bacterial RNA Polymerase Inhibitors

por McPhillie, Martin J., Trowbridge, Rachel, Mariner, Katherine R., O’Neill, Alex J., Johnson, A. Peter, Chopra, Ian, Fishwick, Colin W. G.
Publicado em 2011

The First Small-Molecule Inhibitors of Members of the Ribonuclease E Family

por Kime, Louise, Vincent, Helen A., Gendoo, Deena M. A., Jourdan, Stefanie S., Fishwick, Colin W. G., Callaghan, Anastasia J., McDowall, Kenneth J.
Publicado no Sci Rep (2015)

Erratum: The First Small-Molecule Inhibitors of Members of the Ribonuclease E Family

por Kime, Louise, Vincent, Helen A., Gendoo, Deena M. A., Jourdan, Stefanie S., Fishwick, Colin W. G., Callaghan, Anastasia J., McDowall, Kenneth J.
Publicado no Sci Rep (2015)

In Silico Design and Biological Evaluation of a Dual Specificity Kinase Inhibitor Targeting Cell Cycle Progression and Angiogenesis

por Latham, Antony M., Kankanala, Jayakanth, Fearnley, Gareth W., Gage, Matthew C., Kearney, Mark T., Homer-Vanniasinkam, Shervanthi, Wheatcroft, Stephen B., Fishwick, Colin W. G., Ponnambalam, Sreenivasan
Publicado no PLoS One (2014)

Identification of Selective Inhibitors of the Potassium Channel Kv1.1–1.2((3)) by High-Throughput Virtual Screening and Automated Patch Clamp

por Wacker, Sören J, Jurkowski, Wiktor, Simmons, Katie J, Fishwick, Colin W G, Johnson, A Peter, Madge, David, Lindahl, Erik, Rolland, Jean-Francois, de Groot, Bert L
Publicado em 2012

Assay Platform for Clinically Relevant Metallo-β-lactamases

por van Berkel, Sander S., Brem, Jürgen, Rydzik, Anna M., Salimraj, Ramya, Cain, Ricky, Verma, Anil, Owens, Raymond J., Fishwick, Colin W. G., Spencer, James, Schofield, Christopher J.
Publicado em 2013

X-ray and cryo-EM structures of inhibitor-bound cytochrome bc (1) complexes for structure-based drug discovery

por Amporndanai, Kangsa, Johnson, Rachel M., O’Neill, Paul M., Fishwick, Colin W. G., Jamson, Alexander H., Rawson, Shaun, Muench, Stephen P., Hasnain, S. Samar, Antonyuk, Svetlana V.
Publicado no IUCrJ (2018)

Structure Guided Development of Potent Reversibly Binding Penicillin Binding Protein Inhibitors

por Woon, Esther C. Y., Zervosen, Astrid, Sauvage, Eric, Simmons, Katie J., Živec, Matej, Inglis, Steven R., Fishwick, Colin W. G., Gobec, Stanislav, Charlier, Paulette, Luxen, André, Schofield, Christopher J.
Publicado em 2011

Structural basis of metallo-β-lactamase, serine-β-lactamase and penicillin-binding protein inhibition by cyclic boronates

por Brem, Jürgen, Cain, Ricky, Cahill, Samuel, McDonough, Michael A., Clifton, Ian J., Jiménez-Castellanos, Juan-Carlos, Avison, Matthew B., Spencer, James, Fishwick, Colin W. G., Schofield, Christopher J.
Publicado no Nat Commun (2016)

Cyclic Boronates Inhibit All Classes of β-Lactamases

por Cahill, Samuel T., Cain, Ricky, Wang, David Y., Lohans, Christopher T., Wareham, David W., Oswin, Henry P., Mohammed, Jabril, Spencer, James, Fishwick, Colin W. G., McDonough, Michael A., Schofield, Christopher J., Brem, Jürgen
Publicado no Antimicrob Agents Chemother (2017)