Epoxide based inhibitors of the hepatitis C virus non-structural 2 autoprotease

gan Shaw, Joseph, Fishwick, Colin W.G., Harris, Mark
Cyhoeddwyd yn Antiviral Res (2015)

Identification of a lead like inhibitor of the hepatitis C virus non-structural NS2 autoprotease

gan Shaw, Joseph, Harris, Mark, Fishwick, Colin W.G.
Cyhoeddwyd yn Antiviral Res (2015)

Linezolid and Tiamulin Cross-Resistance in Staphylococcus aureus Mediated by Point Mutations in the Peptidyl Transferase Center

gan Miller, Keith, Dunsmore, Colin J., Fishwick, Colin W. G., Chopra, Ian
Cyhoeddwyd 2008

Identification of an Indazole-Based Pharmacophore for the Inhibition of FGFR Kinases Using Fragment-Led de Novo Design

gan Turner, Lewis D., Summers, Abbey J., Johnson, Laura O., Knowles, Margaret A., Fishwick, Colin W. G.
Cyhoeddwyd yn ACS Med Chem Lett (2017)

Selective Phosphonylation of 5′-Adenosine Monophosphate (5′-AMP) via Pyrophosphite [PPi(III)]

gan Kaye, Karl, Bryant, David E., Marriott, Katie E. R., Ohara, Shohei, Fishwick, Colin W. G., Kee, Terence P.
Cyhoeddwyd yn Orig Life Evol Biosph (2016)

Activity of and Development of Resistance to Corallopyronin A, an Inhibitor of RNA Polymerase

gan Mariner, Katherine, McPhillie, Martin, Trowbridge, Rachel, Smith, Catriona, O'Neill, Alex J., Fishwick, Colin W. G., Chopra, Ian
Cyhoeddwyd 2011

Determinants of Hepatitis C Virus p7 Ion Channel Function and Drug Sensitivity Identified In Vitro

gan StGelais, Corine, Foster, Toshana L., Verow, Mark, Atkins, Elizabeth, Fishwick, Colin W. G., Rowlands, David, Harris, Mark, Griffin, Stephen
Cyhoeddwyd 2009

Furanyl-Rhodanines Are Unattractive Drug Candidates for Development as Inhibitors of Bacterial RNA Polymerase

gan Mariner, Katherine R., Trowbridge, Rachel, Agarwal, Anil K., Miller, Keith, O'Neill, Alex J., Fishwick, Colin W. G., Chopra, Ian
Cyhoeddwyd 2010

Structure-Based Identification and Characterization of Inhibitors of the Epilepsy-Associated K(Na)1.1 (KCNT1) Potassium Channel

gan Cole, Bethan A., Johnson, Rachel M., Dejakaisaya, Hattapark, Pilati, Nadia, Fishwick, Colin W.G., Muench, Stephen P., Lippiat, Jonathan D.
Cyhoeddwyd yn iScience (2020)

Structure-switching M(3)L(2) Ir(iii) coordination cages with photo-isomerising azo-aromatic linkers

gan Oldknow, Samuel, Martir, Diego Rota, Pritchard, Victoria E., Blitz, Mark A., Fishwick, Colin W. G., Zysman-Colman, Eli, Hardie, Michaele J.
Cyhoeddwyd yn Chem Sci (2018)

Structure-Based Ligand Design of Novel Bacterial RNA Polymerase Inhibitors

gan McPhillie, Martin J., Trowbridge, Rachel, Mariner, Katherine R., O’Neill, Alex J., Johnson, A. Peter, Chopra, Ian, Fishwick, Colin W. G.
Cyhoeddwyd 2011

The First Small-Molecule Inhibitors of Members of the Ribonuclease E Family

gan Kime, Louise, Vincent, Helen A., Gendoo, Deena M. A., Jourdan, Stefanie S., Fishwick, Colin W. G., Callaghan, Anastasia J., McDowall, Kenneth J.
Cyhoeddwyd yn Sci Rep (2015)

Erratum: The First Small-Molecule Inhibitors of Members of the Ribonuclease E Family

gan Kime, Louise, Vincent, Helen A., Gendoo, Deena M. A., Jourdan, Stefanie S., Fishwick, Colin W. G., Callaghan, Anastasia J., McDowall, Kenneth J.
Cyhoeddwyd yn Sci Rep (2015)

In Silico Design and Biological Evaluation of a Dual Specificity Kinase Inhibitor Targeting Cell Cycle Progression and Angiogenesis

gan Latham, Antony M., Kankanala, Jayakanth, Fearnley, Gareth W., Gage, Matthew C., Kearney, Mark T., Homer-Vanniasinkam, Shervanthi, Wheatcroft, Stephen B., Fishwick, Colin W. G., Ponnambalam, Sreenivasan
Cyhoeddwyd yn PLoS One (2014)

Identification of Selective Inhibitors of the Potassium Channel Kv1.1–1.2((3)) by High-Throughput Virtual Screening and Automated Patch Clamp

gan Wacker, Sören J, Jurkowski, Wiktor, Simmons, Katie J, Fishwick, Colin W G, Johnson, A Peter, Madge, David, Lindahl, Erik, Rolland, Jean-Francois, de Groot, Bert L
Cyhoeddwyd 2012

Assay Platform for Clinically Relevant Metallo-β-lactamases

gan van Berkel, Sander S., Brem, Jürgen, Rydzik, Anna M., Salimraj, Ramya, Cain, Ricky, Verma, Anil, Owens, Raymond J., Fishwick, Colin W. G., Spencer, James, Schofield, Christopher J.
Cyhoeddwyd 2013

X-ray and cryo-EM structures of inhibitor-bound cytochrome bc (1) complexes for structure-based drug discovery

gan Amporndanai, Kangsa, Johnson, Rachel M., O’Neill, Paul M., Fishwick, Colin W. G., Jamson, Alexander H., Rawson, Shaun, Muench, Stephen P., Hasnain, S. Samar, Antonyuk, Svetlana V.
Cyhoeddwyd yn IUCrJ (2018)

Structure Guided Development of Potent Reversibly Binding Penicillin Binding Protein Inhibitors

gan Woon, Esther C. Y., Zervosen, Astrid, Sauvage, Eric, Simmons, Katie J., Živec, Matej, Inglis, Steven R., Fishwick, Colin W. G., Gobec, Stanislav, Charlier, Paulette, Luxen, André, Schofield, Christopher J.
Cyhoeddwyd 2011

Structural basis of metallo-β-lactamase, serine-β-lactamase and penicillin-binding protein inhibition by cyclic boronates

gan Brem, Jürgen, Cain, Ricky, Cahill, Samuel, McDonough, Michael A., Clifton, Ian J., Jiménez-Castellanos, Juan-Carlos, Avison, Matthew B., Spencer, James, Fishwick, Colin W. G., Schofield, Christopher J.
Cyhoeddwyd yn Nat Commun (2016)

Cyclic Boronates Inhibit All Classes of β-Lactamases

gan Cahill, Samuel T., Cain, Ricky, Wang, David Y., Lohans, Christopher T., Wareham, David W., Oswin, Henry P., Mohammed, Jabril, Spencer, James, Fishwick, Colin W. G., McDonough, Michael A., Schofield, Christopher J., Brem, Jürgen
Cyhoeddwyd yn Antimicrob Agents Chemother (2017)