Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy

Por Fillmore, Christine M, Kuperwasser, Charlotte
Publicado em 2008

Lung Stem and Progenitor Cells in Tissue Homeostasis and Disease

Por Leeman, Kristen T., Fillmore, Christine M., Kim, Carla F.
Publicado em 2014

The Bed and the Bugs: Interactions between the Tumor Microenvironment and Cancer Stem Cells

Por Castaño, Zafira, Fillmore, Christine M., Kim, Carla F., McAllister, Sandra S.
Publicado em 2012

Non-small-cell lung cancers: a heterogeneous set of diseases

Por Chen, Zhao, Fillmore, Christine M., Hammerman, Peter S., Kim, Carla F., Wong, Kwok-Kin
Publicado no Nat Rev Cancer (2014)

Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling

Por Fillmore, Christine M., Gupta, Piyush B., Rudnick, Jenny A., Caballero, Silvia, Keller, Patricia J., Lander, Eric S., Kuperwasser, Charlotte
Publicado em 2010

EZH2 inhibition sensitizes BRG1 and EGFR mutant lung tumors to TopoII inhibitors

Por Fillmore, Christine M., Xu, Chunxiao, Desai, Pooja T., Berry, Joanne M., Rowbotham, Samuel P., Lin, Yi-Jang, Zhang, Haikuo, Marquez, Victor E., Hammerman, Peter S., Wong, Kwok-Kin, Kim, Carla F.
Publicado no Nature (2015)

Inactivation of the Snf5 tumor suppressor stimulates cell cycle progression and cooperates with p53 loss in oncogenic transformation

Por Isakoff, Michael S., Sansam, Courtney G., Tamayo, Pablo, Subramanian, Aravind, Evans, Julia A., Fillmore, Christine M., Wang, Xi, Biegel, Jaclyn A., Pomeroy, Scott L., Mesirov, Jill P., Roberts, Charles W. M.
Publicado em 2005

Tumor-propagating cells and Yap/Taz activity contribute to lung tumor progression and metastasis

Por Lau, Allison N, Curtis, Stephen J, Fillmore, Christine M, Rowbotham, Samuel P, Mohseni, Morvarid, Wagner, Darcy E, Beede, Alexander M, Montoro, Daniel T, Sinkevicius, Kerstin W, Walton, Zandra E, Barrios, Juliana, Weiss, Daniel J, Camargo, Fernando D, Wong, Kwok-Kin, Kim, Carla F
Publicado em 2014

Tumor-propagating cells and Yap/Taz activity contribute to lung tumor progression and metastasis

Por Lau, Allison N, Curtis, Stephen J, Fillmore, Christine M, Rowbotham, Samuel P, Mohseni, Morvarid, Wagner, Darcy E, Beede, Alexander M, Montoro, Daniel T, Sinkevicius, Kerstin W, Walton, Zandra E, Barrios, Juliana, Weiss, Daniel J, Camargo, Fernando D, Wong, Kwok-Kin, Kim, Carla F
Publicado em 2014

Neurotrophin receptor TrkB promotes lung adenocarcinoma metastasis

Por Sinkevicius, Kerstin W., Kriegel, Christina, Bellaria, Kelly J., Lee, Jaewon, Lau, Allison N., Leeman, Kristen T., Zhou, Pengcheng, Beede, Alexander M., Fillmore, Christine M., Caswell, Deborah, Barrios, Juliana, Wong, Kwok-Kin, Sholl, Lynette M., Schlaeger, Thorsten M., Bronson, Roderick T., Chirieac, Lucian R., Winslow, Monte M., Haigis, Marcia C., Kim, Carla F.
Publicado em 2014

Lung stem cell self-renewal relies on Bmi1-dependent control of expression at imprinted loci

Por Zacharek, Sima J., Fillmore, Christine M., Lau, Allison N., Gludish, David W., Chou, Alan, Ho, Joshua W. K., Zamponi, Raffaella, Gazit, Roi, Bock, Christoph, Jäger, Natalie, Smith, Zachary D., Kim, Tae-min, Saunders, Arven H., Wong, Janice, Lee, Joo-Hyeon, Roach, Rebecca R., Rossi, Derrick J., Meissner, Alex, Gimelbrant, Alexander A., Park, Peter J., Kim, Carla F.
Publicado em 2011

Loss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated PD-L1 Expression

Por Xu, Chunxiao, Fillmore, Christine M., Koyama, Shohei, Wu, Hongbo, Zhao, Yanqiu, Chen, Zhao, Herter-Sprie, Grit S., Akbay, Esra A., Tchaicha, Jeremy H., Altabef, Abigail, Reibel, Jacob B., Walton, Zandra, Ji, Hongbin, Watanabe, Hideo, Jänne, Pasi A., Castrillon, Diego H., Rustgi, Anil K., Bass, Adam J., Freeman, Gordon J., Padera, Robert F., Dranoff, Glenn, Hammerman, Peter S., Kim, Carla F., Wong, Kwok-Kin
Publicado em 2014

Oncogenic deregulation of EZH2 as an opportunity for targeted therapy in lung cancer

Por Zhang, Haikuo, Qi, Jun, Reyes, Jaime M., Li, Lewyn, Rao, Prakash K., Li, Fugen, Lin, Charles Y., Perry, Jennifer A., Lawlor, Matthew A., Federation, Alexander, De Raedt, Thomas, Li, Yvonne Y., Liu, Yan, Duarte, Melissa A., Zhang, Yanxi, Herter-Sprie, Grit S., Kikuchi, Eiki, Carretero, Julian, Perou, Charles M., Reibel, Jacob B., Paulk, Joshiawa, Bronson, Roderick T., Watanabe, Hideo, Fillmore, Christine M., Kim, Carla F., Hammerman, Peter S., Brown, Myles, Cichowski, Karen, Long, Henry, Bradner, James E., Wong, Kwok-Kin
Publicado no Cancer Discov (2016)