Neurotrophin receptor TrkB promotes lung adenocarcinoma metastasis

Lung cancer is notorious for its ability to metastasize, but the pathways regulating lung cancer metastasis are largely unknown. An in vitro system designed to discover factors critical for lung cancer cell migration identified brain-derived neurotrophic factor, which stimulates cell migration throu...

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Autori principali: Sinkevicius, Kerstin W., Kriegel, Christina, Bellaria, Kelly J., Lee, Jaewon, Lau, Allison N., Leeman, Kristen T., Zhou, Pengcheng, Beede, Alexander M., Fillmore, Christine M., Caswell, Deborah, Barrios, Juliana, Wong, Kwok-Kin, Sholl, Lynette M., Schlaeger, Thorsten M., Bronson, Roderick T., Chirieac, Lucian R., Winslow, Monte M., Haigis, Marcia C., Kim, Carla F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2014
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104911/
https://ncbi.nlm.nih.gov/pubmed/24982195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1404399111
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