Cancer Stem Cells and the Slow Cycling Phenotype: How to Cut the Gordian Knot Driving Resistance to Therapy in Melanoma

par Fattore, Luigi, Mancini, Rita, Ciliberto, Gennaro
Publié dans Cancers (Basel) (2020)

Single cell analysis to dissect molecular heterogeneity and disease evolution in metastatic melanoma

par Fattore, Luigi, Ruggiero, Ciro Francesco, Liguoro, Domenico, Mancini, Rita, Ciliberto, Gennaro
Publié dans Cell Death Dis (2019)

The Promise of Liquid Biopsy to Predict Response to Immunotherapy in Metastatic Melanoma

par Fattore, Luigi, Ruggiero, Ciro Francesco, Liguoro, Domenico, Castaldo, Vittorio, Catizone, Angiolina, Ciliberto, Gennaro, Mancini, Rita
Publié dans Front Oncol (2021)

MicroRNAs in melanoma development and resistance to target therapy

par Fattore, Luigi, Costantini, Susan, Malpicci, Debora, Ruggiero, Ciro Francesco, Ascierto, Paolo Antonio, Croce, Carlo M., Mancini, Rita, Ciliberto, Gennaro
Publié dans Oncotarget (2017)

Reverse transcriptase inhibition potentiates target therapy in BRAF-mutant melanomas: effects on cell proliferation, apoptosis, DNA-damage, ROS induction and mitochondrial membrane...

par Fattore, Luigi, Malpicci, Debora, Milite, Ciro, Castellano, Sabrina, Sbardella, Gianluca, Botti, Gerardo, Ascierto, Paolo A., Mancini, Rita, Ciliberto, Gennaro
Publié dans Cell Commun Signal (2020)

c-Src Recruitment is Involved in c-MET-Mediated Malignant Behaviour of NT2D1 Non-Seminoma Cells

par Leonetti, Erica, Gesualdi, Luisa, Corano Scheri, Katia, Dinicola, Simona, Fattore, Luigi, Masiello, Maria Grazia, Cucina, Alessandra, Mancini, Rita, Bizzarri, Mariano, Ricci, Giulia, Catizone, Angela
Publié dans Int J Mol Sci (2019)

In Vitro Biophysical and Biological Characterization of Lipid Nanoparticles Co-Encapsulating Oncosuppressors miR-199b-5p and miR-204-5p as Potentiators of Target Therapy in Metasta...

par Fattore, Luigi, Campani, Virginia, Ruggiero, Ciro Francesco, Salvati, Valentina, Liguoro, Domenico, Scotti, Lorena, Botti, Gerardo, Ascierto, Paolo Antonio, Mancini, Rita, De Rosa, Giuseppe, Ciliberto, Gennaro
Publié dans Int J Mol Sci (2020)

Activation of an early feedback survival loop involving phospho-ErbB3 is a general response of melanoma cells to RAF/MEK inhibition and is abrogated by anti-ErbB3 antibodies

par Fattore, Luigi, Marra, Emanuele, Pisanu, Maria Elena, Noto, Alessia, de Vitis, Claudia, Belleudi, Francesca, Aurisicchio, Luigi, Mancini, Rita, Torrisi, Maria Rosaria, Ascierto, Paolo Antonio, Ciliberto, Gennaro
Publié 2013

Activation of the ErbB3-AKT axis promotes melanoma cell survival and proliferation in response to RAF/MEK inhibition

par Fattore, Luigi, Marra, Emanuele, Pisanu, Maria Elena, Noto, Alessia, De Vitis, Claudia, Belleudi, Francesca, Aurisicchio, Luigi, Mancini, Rita, Torrisi, Maria Rosaria, Ascierto, Paolo Antonio, Ciliberto, Gennaro
Publié 2014

ErbB3 plays a key role in the early phase of establishment of resistance to BRAF and/or MEK inhibitors

par Fattore, Luigi, Malpicci, Debora, Marra, Emanuele, Camerlingo, Rosalba, Roscilli, Giuseppe, Belleudi, Francesca, Ribas, Antoni, Mancini, Rita, Torrisi, Maria Rosaria, Aurisicchio, Luigi, Ascierto, Paolo Antonio, Ciliberto, Gennaro
Publié dans J Transl Med (2015)

Selective targeting of point-mutated KRAS through artificial microRNAs

par Acunzo, Mario, Romano, Giulia, Nigita, Giovanni, Veneziano, Dario, Fattore, Luigi, Laganà, Alessandro, Zanesi, Nicola, Fadda, Paolo, Fassan, Matteo, Rizzotto, Lara, Kladney, Raleigh, Coppola, Vincenzo, Croce, Carlo M.
Publié dans Proc Natl Acad Sci U S A (2017)

ErbB3 Phosphorylation as Central Event in Adaptive Resistance to Targeted Therapy in Metastatic Melanoma: Early Detection in CTCs during Therapy and Insights into Regulation by Aut...

par Ruggiero, Ciro Francesco, Malpicci, Debora, Fattore, Luigi, Madonna, Gabriele, Vanella, Vito, Mallardo, Domenico, Liguoro, Domenico, Salvati, Valentina, Capone, Mariaelena, Bedogni, Barbara, Ascierto, Paolo Antonio, Mancini, Rita, Ciliberto, Gennaro
Publié dans Cancers (Basel) (2019)

Combination therapy with anti-ErbB3 monoclonal antibodies and EGFR TKIs potently inhibits Non-small Cell Lung Cancer

par Noto, Alessia, De Vitis, Claudia, Roscilli, Giuseppe, Fattore, Luigi, Malpicci, Debora, Marra, Emanuele, Luberto, Laura, D'Andrilli, Antonio, Coluccia, Pierpaolo, Giovagnoli, Maria Rosaria, Normanno, Nicola, Ruco, Luigi, Aurisicchio, Luigi, Mancini, Rita, Ciliberto, Gennaro
Publié 2013

TrkB is responsible for EMT transition in malignant pleural effusions derived cultures from adenocarcinoma of the lung

par Ricci, Alberto, De Vitis, Claudia, Noto, Alessia, Fattore, Luigi, Mariotta, Salvatore, Cherubini, Emanuela, Roscilli, Giuseppe, Liguori, Giuseppina, Scognamiglio, Giosuè, Rocco, Gaetano, Botti, Gerardo, Giarnieri, Enrico, Giovagnoli, Maria Rosaria, De Toma, Giorgio, Ciliberto, Gennaro, Mancini, Rita
Publié 2013

miR-579-3p controls melanoma progression and resistance to target therapy

par Fattore, Luigi, Mancini, Rita, Acunzo, Mario, Romano, Giulia, Laganà, Alessandro, Pisanu, Maria Elena, Malpicci, Debora, Madonna, Gabriele, Mallardo, Domenico, Capone, Marilena, Fulciniti, Franco, Mazzucchelli, Luca, Botti, Gerardo, Croce, Carlo M., Ascierto, Paolo Antonio, Ciliberto, Gennaro
Publié dans Proc Natl Acad Sci U S A (2016)

microRNA-378a-5p iS a novel positive regulator of melanoma progression

par Tupone, Maria Grazia, D’Aguanno, Simona, Di Martile, Marta, Valentini, Elisabetta, Desideri, Marianna, Trisciuoglio, Daniela, Donzelli, Sara, Sacconi, Andrea, Buglioni, Simonetta, Ercolani, Cristiana, Biagioni, Alessio, Fibbi, Gabriella, Fattore, Luigi, Mancini, Rita, Ciliberto, Gennaro, Blandino, Giovanni, Del Bufalo, Donatella
Publié dans Oncogenesis (2020)

Combination of antibodies directed against different ErbB3 surface epitopes prevents the establishment of resistance to BRAF/MEK inhibitors in melanoma

par Fattore, Luigi, Malpicci, Debora, Marra, Emanuele, Belleudi, Francesca, Noto, Alessia, De Vitis, Claudia, Pisanu, Maria Elena, Coluccia, Pierpaolo, Camerlingo, Rosa, Roscilli, Giuseppe, Ribas, Antoni, Di Napoli, Arianna, Torrisi, Maria Rosaria, Aurisicchio, Luigi, Ascierto, Paolo Antonio, Mancini, Rita, Ciliberto, Gennaro
Publié dans Oncotarget (2015)

CytoMatrix for a reliable and simple characterization of lung cancer stem cells from malignant pleural effusions

par Bruschini, Sara, di Martino, Simona, Pisanu, Maria Elena, Fattore, Luigi, De Vitis, Claudia, Laquintana, Valentina, Buglioni, Simonetta, Tabbì, Eugenio, Cerri, Andrea, Visca, Paolo, Alessandrini, Gabriele, Facciolo, Francesco, Napoli, Christian, Trombetta, Marcella, Santoro, Antonio, Crescenzi, Anna, Ciliberto, Gennaro, Mancini, Rita
Publié dans J Cell Physiol (2019)

Reprogramming miRNAs global expression orchestrates development of drug resistance in BRAF mutated melanoma

par Fattore, Luigi, Ruggiero, Ciro Francesco, Pisanu, Maria Elena, Liguoro, Domenico, Cerri, Andrea, Costantini, Susan, Capone, Francesca, Acunzo, Mario, Romano, Giulia, Nigita, Giovanni, Mallardo, Domenico, Ragone, Concetta, Carriero, Maria Vincenza, Budillon, Alfredo, Botti, Gerardo, Ascierto, Paolo Antonio, Mancini, Rita, Ciliberto, Gennaro
Publié dans Cell Death Differ (2018)

Inhibition of Stearoyl-CoA desaturase 1 reverts BRAF and MEK inhibition-induced selection of cancer stem cells in BRAF-mutated melanoma

par Pisanu, Maria Elena, Maugeri-Saccà, Marcello, Fattore, Luigi, Bruschini, Sara, De Vitis, Claudia, Tabbì, Eugenio, Bellei, Barbara, Migliano, Emilia, Kovacs, Daniela, Camera, Emanuela, Picardo, Mauro, Jakopin, Ziga, Cippitelli, Claudia, Bartolazzi, Armando, Raffa, Salvatore, Torrisi, Maria Rosaria, Fulciniti, Franco, Ascierto, Paolo A., Ciliberto, Gennaro, Mancini, Rita
Publié dans J Exp Clin Cancer Res (2018)