Activation of the ErbB3-AKT axis promotes melanoma cell survival and proliferation in response to RAF/MEK inhibition

অনুরূপ উপাদানগুলি

• Activation of an early feedback survival loop involving phospho-ErbB3 is a general response of melanoma cells to RAF/MEK inhibition and is abrogated by anti-ErbB3 antibodies
  অনুযায়ী: Fattore, Luigi, অন্যান্য
  প্রকাশিত: (2013)
• ErbB3 plays a key role in the early phase of establishment of resistance to BRAF and/or MEK inhibitors
  অনুযায়ী: Fattore, Luigi, অন্যান্য
  প্রকাশিত: (2015)
• Combination of antibodies directed against different ErbB3 surface epitopes prevents the establishment of resistance to BRAF/MEK inhibitors in melanoma
  অনুযায়ী: Fattore, Luigi, অন্যান্য
  প্রকাশিত: (2015)
• The promise of anti-ErbB3 monoclonals as new cancer therapeutics
  অনুযায়ী: Aurisicchio, Luigi, অন্যান্য
  প্রকাশিত: (2012)
• Combination therapy with anti-ErbB3 monoclonal antibodies and EGFR TKIs potently inhibits Non-small Cell Lung Cancer
  অনুযায়ী: Noto, Alessia, অন্যান্য
  প্রকাশিত: (2013)