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The promise of anti-ErbB3 monoclonals as new cancer therapeutics

In the last 3-5 years strong evidence has been gathered demonstrating ErbB3 as a key node for the progression of several cancer types. From the mechanistic standpoint the intracellular region of this receptor is rich of tyrosine residues that, upon phosphorylation, become high affinity binding sites...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Aurisicchio, Luigi, Marra, Emanuele, Roscilli, Giuseppe, Mancini, Rita, Ciliberto, Gennaro
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478453/
https://ncbi.nlm.nih.gov/pubmed/22889873
Etiketak: Etiketa erantsi
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