Nucleophilic compounds decrease advanced glycation end products (AGEs) from ascorbic acid in the hSVCT2 transgenic mouse model of lenticular aging

Por Fan, Xingjun, Monnier, Vincent M
Publicado em 2008

Vitamin C–mediated Maillard Reaction in the Lens Probed in a Transgenic-mouse Model

Por Fan, Xingjun, Monnier, Vincent M.
Publicado em 2008

Lens Glutathione Homeostasis: Discrepancies and gaps in knowledge standing in the way of novel therapeutic approaches

Por Fan, Xingjun, Monnier, Vincent M., Whitson, Jeremy
Publicado no Exp Eye Res (2016)

Binding of Recombinant but Not Endogenous Prion Protein to DNA Causes DNA Internalization and Expression in Mammalian Cells

Por Yin, Shaoman, Fan, Xingjun, Yu, Shuiliang, Li, Chaoyang, Sy, Man-Sun
Publicado em 2008

Identification of Glucose-Derived Cross-Linking Sites in Ribonuclease A

Por Dai, Zhenyu, Wang, Benlian, Sun, Gang, Fan, Xingjun, Anderson, Vernon E., Monnier, Vincent M.
Publicado em 2008

Topical application of L-arginine blocks advanced glycation by ascorbic acid in the lens of hSVCT2 transgenic mice

Por Fan, Xingjun, Xiaoqin, Liu, Potts, Breshey, Strauch, Christopher M., Nemet, Ina, Monnier, Vincent M.
Publicado em 2011

The LEGSKO Mouse: A Mouse Model of Age-Related Nuclear Cataract Based on Genetic Suppression of Lens Glutathione Synthesis

Por Fan, Xingjun, Liu, Xiaoqin, Hao, Shuyu, Wang, Benlian, Robinson, Michael L., Monnier, Vincent M.
Publicado em 2012

Evidence of Dual Mechanisms of Glutathione Uptake in the Rodent Lens: A Novel Role for Vitreous Humor in Lens Glutathione Homeostasis

Por Whitson, Jeremy A., Sell, David R., Goodman, Michael C., Monnier, Vincent M., Fan, Xingjun
Publicado no Invest Ophthalmol Vis Sci (2016)

Proteomic Analysis of the Glutathione-Deficient LEGSKO Mouse Lens Reveals Activation of EMT Signaling, Loss of Lens Specific Markers, and Changes in Stress Response Proteins

Por Whitson, Jeremy A., Wilmarth, Phillip A., Klimek, John, Monnier, Vincent M., David, Larry, Fan, Xingjun
Publicado no Free Radic Biol Med (2017)

Transcriptome of the GSH-Depleted Lens Reveals Changes in Detoxification and EMT Signaling Genes, Transport Systems, and Lipid Homeostasis

Por Whitson, Jeremy A., Zhang, Xiang, Medvedovic, Mario, Chen, Jenny, Wei, Zongbo, Monnier, Vincent M., Fan, Xingjun
Publicado no Invest Ophthalmol Vis Sci (2017)

UVA Light-excited Kynurenines Oxidize Ascorbate and Modify Lens Proteins through the Formation of Advanced Glycation End Products: IMPLICATIONS FOR HUMAN LENS AGING AND CATARACT FO...

Por Linetsky, Mikhail, Raghavan, Cibin T., Johar, Kaid, Fan, Xingjun, Monnier, Vincent M., Vasavada, Abhay R., Nagaraj, Ram H.
Publicado em 2014

The oxidized thiol proteome in aging and cataractous mouse and human lens revealed by ICAT labeling

Por Wang, Benlian, Hom, Grant, Zhou, Sheng, Guo, Minfei, Li, Binbin, Yang, Jing, Monnier, Vincent M., Fan, Xingjun
Publicado no Aging Cell (2016)

Presence of retinal pericyte-reactive autoantibodies in diabetic retinopathy patients

Por Zhang, Lingjun, Li, Yan, Payne, John, Srivastava, Sunil, Fan, Xingjun, Fung, John, Li, Xiaorong, Kern, Timothy S., Lin, Feng
Publicado no Sci Rep (2016)

Reduced Glutathione Level Promotes Epithelial-Mesenchymal Transition in Lens Epithelial Cells via a Wnt/β-Catenin–Mediated Pathway: Relevance for Cataract Therapy

Por Wei, Zongbo, Caty, Jane, Whitson, Jeremy, Zhang, Amy D., Srinivasagan, Ramkumar, Kavanagh, Terrance J., Yan, Hong, Fan, Xingjun
Publicado no Am J Pathol (2017)

Evidence of Highly Conserved β-Crystallin Disulfidome that Can be Mimicked by In Vitro Oxidation in Age-related Human Cataract and Glutathione Depleted Mouse Lens

Por Fan, Xingjun, Zhou, Sheng, Wang, Benlian, Hom, Grant, Guo, Minfei, Li, Binbin, Yang, Jing, Vaysburg, Dennis, Monnier, Vincent M
Publicado no Mol Cell Proteomics (2015)

Mechanism of Lysine Oxidation in Human Lens Crystallins during Aging and in Diabetes

Por Fan, Xingjun, Zhang, Jianye, Theves, Mathilde, Strauch, Christopher, Nemet, Ina, Liu, Xiaoqin, Qian, Juan, Giblin, Frank J., Monnier, Vincent M.
Publicado em 2009

Vitamin C mediates chemical aging of lens crystallins by the Maillard reaction in a humanized mouse model

Por Fan, Xingjun, Reneker, Lixing W., Obrenovich, Mark E., Strauch, Christopher, Cheng, Rongzhu, Jarvis, Simon M., Ortwerth, Beryl J., Monnier, Vincent M.
Publicado em 2006

ANAEROBIC VS. AEROBIC PATHWAYS OF CARBONYL AND OXIDANT STRESS IN HUMAN LENS AND SKIN DURING AGING AND IN DIABETES: A COMPARATIVE ANALYSIS

Por Fan, Xingjun, Sell, David R, Zhang, Jianye, Nemet, Ina, Theves, Mathilde, Lu, Jie, Strauch, Christopher, Halushka, Marc K., Monnier, Vincent M.
Publicado em 2010