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Reduced Glutathione Level Promotes Epithelial-Mesenchymal Transition in Lens Epithelial Cells via a Wnt/β-Catenin–Mediated Pathway: Relevance for Cataract Therapy

The epithelial-mesenchymal transition (EMT) process plays a pivotal role in the pathogenesis of posterior capsular opacification because of remnant lens epithelial cell proliferation, migration, and transformation after cataract surgery. The latter, we hypothesize, may result in posterior capsule wr...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Wei, Zongbo, Caty, Jane, Whitson, Jeremy, Zhang, Amy D., Srinivasagan, Ramkumar, Kavanagh, Terrance J., Yan, Hong, Fan, Xingjun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809338/
https://ncbi.nlm.nih.gov/pubmed/28827139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.07.018
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