Reduced Glutathione Level Promotes Epithelial-Mesenchymal Transition in Lens Epithelial Cells via a Wnt/β-Catenin–Mediated Pathway: Relevance for Cataract Therapy

The epithelial-mesenchymal transition (EMT) process plays a pivotal role in the pathogenesis of posterior capsular opacification because of remnant lens epithelial cell proliferation, migration, and transformation after cataract surgery. The latter, we hypothesize, may result in posterior capsule wr...

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Pubblicato in:Am J Pathol
Autori principali: Wei, Zongbo, Caty, Jane, Whitson, Jeremy, Zhang, Amy D., Srinivasagan, Ramkumar, Kavanagh, Terrance J., Yan, Hong, Fan, Xingjun
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809338/
https://ncbi.nlm.nih.gov/pubmed/28827139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.07.018
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