Reduced Glutathione Level Promotes Epithelial-Mesenchymal Transition in Lens Epithelial Cells via a Wnt/β-Catenin–Mediated Pathway: Relevance for Cataract Therapy

The epithelial-mesenchymal transition (EMT) process plays a pivotal role in the pathogenesis of posterior capsular opacification because of remnant lens epithelial cell proliferation, migration, and transformation after cataract surgery. The latter, we hypothesize, may result in posterior capsule wr...

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izdano v:Am J Pathol
Main Authors: Wei, Zongbo, Caty, Jane, Whitson, Jeremy, Zhang, Amy D., Srinivasagan, Ramkumar, Kavanagh, Terrance J., Yan, Hong, Fan, Xingjun
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2017
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809338/
https://ncbi.nlm.nih.gov/pubmed/28827139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.07.018
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