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Mechanism of Lysine Oxidation in Human Lens Crystallins during Aging and in Diabetes
Oxidative mechanisms during nuclear sclerosis of the lens are poorly understood, in particular metal-catalyzed oxidation. The lysyl oxidation product adipic semialdehyde (allysine, ALL) and its oxidized end-product 2-aminoadipic acid (2-AAA) were determined as a function of age and presence of diabe...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2787324/ https://ncbi.nlm.nih.gov/pubmed/19854833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.032094 |
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