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Presence of retinal pericyte-reactive autoantibodies in diabetic retinopathy patients

The loss of retinal pericytes (RPCs) is a hallmark of early stage diabetic retinopathy (DR), but the mechanism underlying RPC death is unclear. Although it was postulated in previous studies using bovine RPCs that autoantibodies against RPCs might develop and induce RPC death, it is unknown whether...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Lingjun, Li, Yan, Payne, John, Srivastava, Sunil, Fan, Xingjun, Fung, John, Li, Xiaorong, Kern, Timothy S., Lin, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4738258/
https://ncbi.nlm.nih.gov/pubmed/26839120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20341
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