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Presence of retinal pericyte-reactive autoantibodies in diabetic retinopathy patients

The loss of retinal pericytes (RPCs) is a hallmark of early stage diabetic retinopathy (DR), but the mechanism underlying RPC death is unclear. Although it was postulated in previous studies using bovine RPCs that autoantibodies against RPCs might develop and induce RPC death, it is unknown whether...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Zhang, Lingjun, Li, Yan, Payne, John, Srivastava, Sunil, Fan, Xingjun, Fung, John, Li, Xiaorong, Kern, Timothy S., Lin, Feng
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4738258/
https://ncbi.nlm.nih.gov/pubmed/26839120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20341
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