UGT concentrations in human rectal tissue after multidose, oral curcumin

Autor Asher, Gary N., Fallon, John K., Smith, Philip C.
Vydáno v Pharmacol Res Perspect (2016)

Targeted Precise Quantification of 12 Human Recombinant Uridine-Diphosphate Glucuronosyl Transferase 1A and 2B Isoforms Using Nano-Ultra-High-Performance Liquid Chromatography/Tand...

Autor Fallon, John K., Neubert, Hendrik, Goosen, Theunis C., Smith, Philip C.
Vydáno 2013

Extreme low dose of 5-fluorouracil reverses MDR in cancer by sensitizing cancer associated fibroblasts and down-regulating P-gp

Autor Ma, Yan, Wang, Yuhua, Xu, Zhenghong, Wang, Yongjun, Fallon, John K., Liu, Feng
Vydáno v PLoS One (2017)

Differential detergent fractionation of membrane protein from small samples of hepatocytes and liver tissue for quantitative proteomic analysis of drug metabolizing enzymes and tra...

Autor Qasem, Rani J., Fallon, John K., Nautiyal, Manisha, Mosedale, Merrie, Smith, Philip C.
Vydáno v J Pharm Sci (2020)

Evaluation of human primary intestinal monolayers for drug metabolizing capabilities

Autor Speer, Jennifer E., Wang, Yuli, Fallon, John K., Smith, Philip C., Allbritton, Nancy L.
Vydáno v J Biol Eng (2019)

Role of Organic Solute Transporter Alpha/Beta in Hepatotoxic Bile Acid Transport and Drug Interactions

Autor Beaudoin, James J, Bezençon, Jacqueline, Sjöstedt, Noora, Fallon, John K, Brouwer, Kim L R
Vydáno v Toxicol Sci (2020)

Pharmacokinetics of Sequential Doses of Capreomycin Powder for Inhalation in Guinea Pigs

Autor Garcia-Contreras, L., Muttil, Pavan, Fallon, John K., Kabadi, Mohan, Gerety, Robert, Hickey, Anthony J.
Vydáno 2012

New mouse xenograft model modulated by tumor-associated fibroblasts for human multi-drug resistance in cancer

Autor MA, YAN, LIN, ZHIQIANG, FALLON, JOHN K., ZHAO, QIANG, LIU, DAN, WANG, YONGJUN, LIU, FENG
Vydáno v Oncol Rep (2015)

Scaling factors for the in vitro–in vivo extrapolation (IV–IVE) of renal drug and xenobiotic glucuronidation clearance

Autor Knights, Kathleen M., Spencer, Shane M., Fallon, John K., Chau, Nuy, Smith, Philip C., Miners, John O.
Vydáno v Br J Clin Pharmacol (2016)

Targeted quantitative proteomic analysis of drug metabolizing enzymes and transporters by nano LC-MS/MS in the sandwich cultured human hepatocyte model

Autor Khatri, Raju, Fallon, John K., Rementer, Rebecca J. B., Kulick, Natasha T., Lee, Craig R., Smith, Philip C.
Vydáno v J Pharmacol Toxicol Methods (2019)

Expansion of Knowledge on OCT1 Variant Activity In Vitro and In Vivo Using Oct1/2(−/−) Mice

Autor Morse, Bridget L., Chen, Lisa Hong, Catlow, John T., Fallon, John K., Smith, Philip C., Hillgren, Kathleen M.
Vydáno v Front Pharmacol (2021)

The effect of 3,4-methylenedioxymethamphetamine (MDMA, ?ecstasy?) and its metabolites on neurohypophysial hormone release from the isolated rat hypothalamus

Autor Forsling, Mary L, Fallon, John K, Shah, Darshna, Tilbrook, Gary S, Cowan, David A, Kicman, Andrew T, Hutt, Andrew J
Vydáno 2002

Quantification of Human Uridine-Diphosphate Glucuronosyl Transferase (UGT) 1A Isoforms in Liver, Intestine and Kidney using nanoLC-MS/MS

Autor Harbourt, David E, Fallon, John K, Ito, Shinya, Baba, Takashi, Ritter, Joseph K, Glish, Gary L, Smith, Philip C
Vydáno 2011

Combinational Delivery of Hydrophobic and Hydrophilic Anticancer Drugs in Single Nanoemulsions To Treat MDR in Cancer

Autor Ma, Yan, Liu, Dan, Wang, Dun, Wang, Yongjun, Fu, Qiang, Fallon, John K., Yang, Xinggang, He, Zhonggui, Liu, Feng
Vydáno 2014

Quantitative Profiling of Human Renal UDP-glucuronosyltransferases and Glucuronidation Activity: A Comparison of Normal and Tumoral Kidney Tissues

Autor Margaillan, Guillaume, Rouleau, Michèle, Fallon, John K., Caron, Patrick, Villeneuve, Lyne, Turcotte, Véronique, Smith, Philip C., Joy, Melanie S., Guillemette, Chantal
Vydáno v Drug Metab Dispos (2015)

Characterization of Primary Mouse Hepatocyte Spheroids as a Model System to Support Investigations of Drug-Induced Liver Injury

Autor Nautiyal, Manisha, Qasem, Rani J., Fallon, John K., Wolf, Kristina K., Liu, Jingli, Dixon, Darlene, Smith, Philip C., Mosedale, Merrie
Vydáno v Toxicol In Vitro (2020)

Carboxylesterase Activities and Protein Expression in Rabbit and Pig Ocular Tissues

Autor Hammid, Anam, Fallon, John K., Lassila, Toni, Salluce, Giulia, Smith, Philip C., Tolonen, Ari, Sauer, Achim, Urtti, Arto, Honkakoski, Paavo
Vydáno v Mol Pharm (2021)

Multiplexed Targeted Quantitative Proteomics Predicts Hepatic Glucuronidation Potential

Autor Margaillan, Guillaume, Rouleau, Michèle, Klein, Kathrin, Fallon, John K., Caron, Patrick, Villeneuve, Lyne, Smith, Philip C., Zanger, Ulrich M., Guillemette, Chantal
Vydáno v Drug Metab Dispos (2015)

Molecular transport through primary human small intestinal monolayers by culture on a collagen scaffold with a gradient of chemical cross-linking

Autor Speer, Jennifer E., Gunasekara, Dulan B., Wang, Yuli, Fallon, John K., Attayek, Peter J., Smith, Philip C., Sims, Christopher E., Allbritton, Nancy L.
Vydáno v J Biol Eng (2019)

Endogenous Coproporphyrin I and III Are Altered in Multidrug Resistance-Associated Protein 2-Deficient (TR(−)) Rats

Autor Bezençon, Jacqueline, Saran, Chitra, Hussner, Janine, Beaudoin, James J., Zhang, Yueping, Shen, Hong, Fallon, John K., Smith, Philip C., zu Schwabedissen, Henriette E. Meyer, Brouwer, Kim L.R.
Vydáno v J Pharm Sci (2020)