STarFish: A Stacked Ensemble Target Fishing Approach and its Application to Natural Products

Por Cockroft, Nicholas T., Cheng, Xiaolin, Fuchs, James R.
Publicado no J Chem Inf Model (2019)

Rocaglamide, Silvestrol and Structurally Related Bioactive Compounds from Aglaia Species

Por Pan, Li, Woodard, John L., Lucas, David M., Fuchs, James R., Kinghorn, A. Douglas
Publicado em 2014

Site-Selective C–H Functionalization of (Hetero)Arenes via Transient, Non-Symmetric Iodanes

Por Fosu, Stacy C., Hambira, Chido M., Chen, Andrew D., Fuchs, James R., Nagib, David A.
Publicado no Chem (2018)

(15)N Stable Isotope Labeling and Comparative Metabolomics Facilitates Genome Mining in Cultured Cyanobacteria

Por May, Daniel S., Crnkovic, Camila M., Krunic, Aleksej, Wilson, Tyler A., Fuchs, James R., Orjala, Jimmy E.
Publicado no ACS Chem Biol (2020)

Identification of a Small Molecule Anti-biofilm Agent Against Salmonella enterica

Por Moshiri, Jasmine, Kaur, Darpan, Hambira, Chido M., Sandala, Jenna L., Koopman, Jacob A., Fuchs, James R., Gunn, John S.
Publicado no Front Microbiol (2018)

Intramolecular Diels–Alder/1,3-Dipolar Cycloaddition Cascade of 1,3,4-Oxadiazoles

Por Elliott, Gregory I., Fuchs, James R., Blagg, Brian S. J., Ishikawa, Hayato, Tao, Houchao, Yuan, Z.-Q., Boger, Dale L.
Publicado em 2006

TALEN Knockout of the PSIP1 Gene in Human Cells: Analyses of HIV-1 Replication and Allosteric Integrase Inhibitor Mechanism

Por Fadel, Hind J., Morrison, James H., Saenz, Dyana T., Fuchs, James R., Kvaratskhelia, Mamuka, Ekker, Stephen C., Poeschla, Eric M.
Publicado em 2014

Discovery of novel small molecule modulators of Clavibacter michiganensis subsp. michiganensis

Por Xu, Xiulan, Kumar, Anand, Deblais, Loïc, Pina-Mimbela, Ruby, Nislow, Corey, Fuchs, James R., Miller, Sally A., Rajashekara, Gireesh
Publicado no Front Microbiol (2015)

Allosteric HIV‐1 integrase inhibitors promote aberrant protein multimerization by directly mediating inter‐subunit interactions: Structural and thermodynamic modeling studies

Por Deng, Nanjie, Hoyte, Ashley, Mansour, Yara E., Mohamed, Mosaad S., Fuchs, James R., Engelman, Alan N., Kvaratskhelia, Mamuka, Levy, Ronald
Publicado no Protein Sci (2016)

Total Synthesis of Scytonemide A Employing Weinreb AM Solid-Phase Resin

Por Wilson, Tyler A., Tokarski, Robert J., Sullivan, Peter, Demoret, Robert M., Orjala, Jimmy, Rakotondraibe, L. Harinantenaina, Fuchs, James R.
Publicado no J Nat Prod (2018)

Trichormamides A and B with Antiproliferative Activity from the Cultured Freshwater Cyanobacterium Trichormus sp. UIC 10339

Por Luo, Shangwen, Krunic, Aleksej, Kang, Hahk-Soo, Chen, Wei-Lun, Woodard, John L., Fuchs, James R., Swanson, Steven M., Orjala, Jimmy
Publicado em 2014

Computational and synthetic approaches for developing Lavendustin B derivatives as allosteric inhibitors of HIV-1 integrase

Por Agharbaoui, Fatima E., Hoyte, Ashley C., Ferro, Stefania, Gitto, Rosaria, Buemi, Maria Rosa, Fuchs, James R., Kvaratskhelia, Mamuka, De Luca, Laura
Publicado no Eur J Med Chem (2016)

New structural analogues of curcumin exhibit potent growth suppressive activity in human colorectal carcinoma cells

Por Cen, Ling, Hutzen, Brian, Ball, Sarah, DeAngelis, Stephanie, Chen, Chun-Liang, Fuchs, James R, Li, Chenglong, Li, Pui-Kai, Lin, Jiayuh
Publicado em 2009

A Liquid Chromatography –Tandem Mass Spectrometric Method for Quantification of Curcuminoids in Cell Medium and Mouse plasma

Por Saradhi, U.V.R. Vijaya, Ling, Yonghua, Wang, Jiang, Chiu, Ming, Schwartz, Eric B., Fuchs, James R., Chan, Kenneth K., Liu, Zhongfa
Publicado em 2010

Sterols with antileishmanial activity isolated from the roots of Pentalinon andrieuxii

Por Pan, Li, Lezama-Davila, Claudio M., Isaac-Marquez, Angelica P., Calomeni, Edward P., Fuchs, James R., Satoskar, Abhay R., Kinghorn, A. Douglas
Publicado em 2012

A Critical Role of the C-terminal Segment for Allosteric Inhibitor-induced Aberrant Multimerization of HIV-1 Integrase

Por Shkriabai, Nikoloz, Dharmarajan, Venkatasubramanian, Slaughter, Alison, Kessl, Jacques J., Larue, Ross C., Feng, Lei, Fuchs, James R., Griffin, Patrick R., Kvaratskhelia, Mamuka
Publicado em 2014

FLLL12 induces apoptosis in lung cancer cells through a p53/p73-independent but death receptor 5-dependent pathway

Por Haque, Abedul, Rahman, Mohammad A., Fuchs, James R., Chen, Zhuo Georgia, Khuri, Fadlo R., Shin, Dong M., Amin, A.R.M. Ruhul
Publicado no Cancer Lett (2015)

Distribution and Redistribution of HIV-1 Nucleocapsid Protein in Immature, Mature, and Integrase-Inhibited Virions: a Role for Integrase in Maturation

Por Fontana, Juan, Jurado, Kellie A., Cheng, Naiqian, Ly, Ngoc L., Fuchs, James R., Gorelick, Robert J., Engelman, Alan N., Steven, Alasdair C.
Publicado no J Virol (2015)

Potential Anticancer Agents Characterized from Selected Tropical Plants

Por Ren, Yulin, Carcache de Blanco, Esperanza J., Fuchs, James R., Soejarto, Djaja D., Burdette, Joanna E., Swanson, Steven M., Kinghorn, A. Douglas
Publicado no J Nat Prod (2019)

Evaluation of synergy between host and pathogen-directed therapies against intracellular Leishmania donovani

Por Zahid, M. Shamim Hasan, Johnson, Monica M., Tokarski, Robert J., Satoskar, Abhay R., Fuchs, James R., Bachelder, Eric M., Ainslie, Kristy M.
Publicado no Int J Parasitol Drugs Drug Resist (2019)