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FLLL12 induces apoptosis in lung cancer cells through a p53/p73-independent but death receptor 5-dependent pathway

Unlike chemotherapy drugs, the safety of natural compounds such as curcumin has been well established. However, the potential use of curcumin in cancer has been compromised by its low bioavailability, limited tissue distribution and rapid biotransformation leading to low in vivo efficacy. To circumv...

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Bibliographic Details
Published in:Cancer Lett
Main Authors: Haque, Abedul, Rahman, Mohammad A., Fuchs, James R., Chen, Zhuo Georgia, Khuri, Fadlo R., Shin, Dong M., Amin, A.R.M. Ruhul
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433807/
https://ncbi.nlm.nih.gov/pubmed/25917567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2015.04.017
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