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BTK modulates p73 activity to induce apoptosis independently of p53

Bruton’s tyrosine kinase (BTK) is a key component of B cell receptor signalling. Because of this, BTK plays an important role in cell proliferation and survival in various B cell malignancies. However, in certain contexts, BTK can also have tumour suppressor functions. We have previously shown that...

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Detalhes bibliográficos
Publicado no:Cell Death Discov
Main Authors: Rada, Miran, Barlev, Nickolai, Macip, Salvador
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134113/
https://ncbi.nlm.nih.gov/pubmed/30245853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-018-0097-7
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