A Liquid Chromatography –Tandem Mass Spectrometric Method for Quantification of Curcuminoids in Cell Medium and Mouse plasma

Curcumin and tetrahydrocurcumin (THC) have been found as potent DNMT1 inhibitors, but they suffer from low oral bioavailability and rapid metabolism in vivo. To circumvent these problems, two curcumin analogs: 1,7-bis(3,4-dimethoxyphenyl)-4,4-dimethyl-1,6-heptadiene-3,5-dione (TMC) and 1,7-bis(3,4-d...

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Detalhes bibliográficos
Main Authors: Saradhi, U.V.R. Vijaya, Ling, Yonghua, Wang, Jiang, Chiu, Ming, Schwartz, Eric B., Fuchs, James R., Chan, Kenneth K., Liu, Zhongfa
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975763/
https://ncbi.nlm.nih.gov/pubmed/20934924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2010.08.039
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