A Liquid Chromatography –Tandem Mass Spectrometric Method for Quantification of Curcuminoids in Cell Medium and Mouse plasma

Curcumin and tetrahydrocurcumin (THC) have been found as potent DNMT1 inhibitors, but they suffer from low oral bioavailability and rapid metabolism in vivo. To circumvent these problems, two curcumin analogs: 1,7-bis(3,4-dimethoxyphenyl)-4,4-dimethyl-1,6-heptadiene-3,5-dione (TMC) and 1,7-bis(3,4-d...

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Bibliografiset tiedot
Päätekijät: Saradhi, U.V.R. Vijaya, Ling, Yonghua, Wang, Jiang, Chiu, Ming, Schwartz, Eric B., Fuchs, James R., Chan, Kenneth K., Liu, Zhongfa
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975763/
https://ncbi.nlm.nih.gov/pubmed/20934924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2010.08.039
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