A Liquid Chromatography –Tandem Mass Spectrometric Method for Quantification of Curcuminoids in Cell Medium and Mouse plasma

Curcumin and tetrahydrocurcumin (THC) have been found as potent DNMT1 inhibitors, but they suffer from low oral bioavailability and rapid metabolism in vivo. To circumvent these problems, two curcumin analogs: 1,7-bis(3,4-dimethoxyphenyl)-4,4-dimethyl-1,6-heptadiene-3,5-dione (TMC) and 1,7-bis(3,4-d...

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主要な著者: Saradhi, U.V.R. Vijaya, Ling, Yonghua, Wang, Jiang, Chiu, Ming, Schwartz, Eric B., Fuchs, James R., Chan, Kenneth K., Liu, Zhongfa
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975763/
https://ncbi.nlm.nih.gov/pubmed/20934924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2010.08.039
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