Quantification of Regional DNA Methylation by Liquid Chromatography/Tandem Mass Spectrometry

Promoter hypermethylation associated tumor suppressor genes (TSGs) silencing has been explored as a therapeutic target for hypomethylating agents. Promoter methylation change may serve as a pharmacodynamic endpoint for evaluation of the efficacy of these agents and predict the patient’s clinical res...

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Autori principali: Liu, Zhongfa, Wu, Jiejun, Xie, Zhiliang, Liu, Shujun, Fan-Havard, Patty, Huang, Tim H-M, Plass, Christoph, Marcucci, Guido, Chan, Kenneth K
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939067/
https://ncbi.nlm.nih.gov/pubmed/19442645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2009.05.012
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