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Quantification of Regional DNA Methylation by Liquid Chromatography/Tandem Mass Spectrometry
Promoter hypermethylation associated tumor suppressor genes (TSGs) silencing has been explored as a therapeutic target for hypomethylating agents. Promoter methylation change may serve as a pharmacodynamic endpoint for evaluation of the efficacy of these agents and predict the patient’s clinical res...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3939067/ https://ncbi.nlm.nih.gov/pubmed/19442645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2009.05.012 |
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