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Quantification of salsolinol enantiomers by stable isotope dilution liquid chromatography with tandem mass spectrometric detection

Salsolinol, 1-methyl-6,7-dihydroxy-2,3,4,5-tetrahydroisoquinoline (SAL), is a precursor of a Parkinsonian neurotoxin, N-methysalsolinol (N-methyl-SAL). Previous studies have shown that individual enantiomers of N-methyl-SAL possess distinct neurotoxicological properties. In this work, a chiral high-...

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Detalles Bibliográficos
Main Authors: Cai, Min, Liu, Yi-Ming
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839069/
https://ncbi.nlm.nih.gov/pubmed/19034892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rcm.3847
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