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Simultaneous Quantification of Methylated Cytidine and Adenosine in Cellular and Tissue RNA by Nano-Flow Liquid Chromatography-Tandem Mass Spectrometry Coupled with the Stable Isotope-dilution Method

The rising interest in understanding the functions, regulation and maintenance of the epitranscriptome calls for robust and accurate analytical methods for the identification and quantification of post-transcriptionally modified nucleosides in RNA. Mono-methylations of cytidine and adenosine are com...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Fu, Lijuan, Amato, Nicolas J., Wang, Pengcheng, McGowan, Sara J., Niedernhofer, Laura J., Wang, Yinsheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711271/
https://ncbi.nlm.nih.gov/pubmed/26158405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.5b00951
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