Distribution and Redistribution of HIV-1 Nucleocapsid Protein in Immature, Mature, and Integrase-Inhibited Virions: a Role for Integrase in Maturation

During virion maturation, HIV-1 capsid protein assembles into a conical core containing the viral ribonucleoprotein (vRNP) complex, thought to be composed mainly of the viral RNA and nucleocapsid protein (NC). After infection, the viral RNA is reverse transcribed into double-stranded DNA, which is t...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Fontana, Juan, Jurado, Kellie A., Cheng, Naiqian, Ly, Ngoc L., Fuchs, James R., Gorelick, Robert J., Engelman, Alan N., Steven, Alasdair C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577894/
https://ncbi.nlm.nih.gov/pubmed/26178982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01522-15
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