Conserved Cysteines of the Human Immunodeficiency Virus Type 1 Protease Are Involved in Regulation of Polyprotein Processing and Viral Maturation of Immature Virions

We investigated the role of the two highly conserved cysteine residues, cysteines 67 and 95, of the human immunodeficiency virus type 1 (HIV-1) protease in regulating the activity of that protease during viral maturation. To this end, we generated four HIV-1 molecular clones: the wild type, containi...

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Hlavní autoři: Davis, David A., Yusa, Keisuke, Gillim, Laura A., Newcomb, Fonda M., Mitsuya, Hiroaki, Yarchoan, Robert
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1999
Témata:
Structure and Assembly
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC103936/
https://ncbi.nlm.nih.gov/pubmed/9882317
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