Suboptimal inhibition of protease activity in human immunodeficiency virus type 1: Effects on virion morphogenesis and RNA maturation

Protease activity within nascently released human immunodeficiency virus type 1 (HIV-1) particles is responsible for the cleavage of the viral polyproteins Gag and Gag-Pol into their constituent parts, which results in the subsequent condensation of the mature conical core surrounding the viral geno...

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Bibliographische Detailangaben
Hauptverfasser: Moore, Michael D., Fu, William, Soheilian, Ferri, Nagashima, Kunio, Ptak, Roger G., Pathak, Vinay K., Hu, Wei-Shau
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577075/
https://ncbi.nlm.nih.gov/pubmed/18657842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.06.030
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