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Mutation of Dileucine-Like Motifs in the Human Immunodeficiency Virus Type 1 Capsid Disrupts Virus Assembly, Gag-Gag Interactions, Gag-Membrane Binding, and Virion Maturation

The human immunodeficiency virus type 1 (HIV-1) Gag precursor protein Pr55(Gag) drives the assembly and release of virus-like particles in the infected cell. The capsid (CA) domain of Gag plays an important role in these processes by promoting Gag-Gag interactions during assembly. The C-terminal dom...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Joshi, Anjali, Nagashima, Kunio, Freed, Eric O.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2006
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1563813/
https://ncbi.nlm.nih.gov/pubmed/16873251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00355-06
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