The EntF and EntE adenylation domains of Escherichia coli enterobactin synthetase: Sequestration and selectivity in acyl-AMP transfers to thiolation domain cosubstrates

door Ehmann, David E., Shaw-Reid, Cathryn A., Losey, Heather C., Walsh, Christopher T.
Gepubliceerd in 2000

Untargeted Metabolomics To Ascertain Antibiotic Modes of Action

door Vincent, Isabel M., Ehmann, David E., Mills, Scott D., Perros, Manos, Barrett, Michael P.
Gepubliceerd in Antimicrob Agents Chemother (2016)

Target-Based Resistance in Pseudomonas aeruginosa and Escherichia coli to NBTI 5463, a Novel Bacterial Type II Topoisomerase Inhibitor

door Nayar, Asha S., Dougherty, Thomas J., Reck, Folkert, Thresher, Jason, Gao, Ning, Shapiro, Adam B., Ehmann, David E.
Gepubliceerd in Antimicrob Agents Chemother (2014)

Avibactam is a covalent, reversible, non–β-lactam β-lactamase inhibitor

door Ehmann, David E., Jahić, Haris, Ross, Philip L., Gu, Rong-Fang, Hu, Jun, Kern, Gunther, Walkup, Grant K., Fisher, Stewart L.
Gepubliceerd in 2012

NBTI 5463 Is a Novel Bacterial Type II Topoisomerase Inhibitor with Activity against Gram-Negative Bacteria and In Vivo Efficacy

door Dougherty, Thomas J., Nayar, Asha, Newman, Joseph V., Hopkins, Sussie, Stone, Gregory G., Johnstone, Michele, Shapiro, Adam B., Cronin, Mark, Reck, Folkert, Ehmann, David E.
Gepubliceerd in 2014

NBTI 5463 Is a Novel Bacterial Type II Topoisomerase Inhibitor with Activity against Gram-Negative Bacteria and In Vivo Efficacy

door Dougherty, Thomas J., Nayar, Asha, Newman, Joseph V., Hopkins, Sussie, Stone, Gregory G., Johnstone, Michele, Shapiro, Adam B., Cronin, Mark, Reck, Folkert, Ehmann, David E.
Gepubliceerd in 2014

Inhibition of Neisseria gonorrhoeae Type II Topoisomerases by the Novel Spiropyrimidinetrione AZD0914

door Kern, Gunther, Palmer, Tiffany, Ehmann, David E., Shapiro, Adam B., Andrews, Beth, Basarab, Gregory S., Doig, Peter, Fan, Jun, Gao, Ning, Mills, Scott D., Mueller, John, Sriram, Shubha, Thresher, Jason, Walkup, Grant K.
Gepubliceerd in J Biol Chem (2015)

Kinetics of Avibactam Inhibition against Class A, C, and D β-Lactamases

door Ehmann, David E., Jahić, Haris, Ross, Philip L., Gu, Rong-Fang, Hu, Jun, Durand-Réville, Thomas F., Lahiri, Sushmita, Thresher, Jason, Livchak, Stephania, Gao, Ning, Palmer, Tiffany, Walkup, Grant K., Fisher, Stewart L.
Gepubliceerd in 2013

Molecular Mechanisms of Sulbactam Antibacterial Activity and Resistance Determinants in Acinetobacter baumannii

door Penwell, William F., Shapiro, Adam B., Giacobbe, Robert A., Gu, Rong-Fang, Gao, Ning, Thresher, Jason, McLaughlin, Robert E., Huband, Michael D., DeJonge, Boudewijn L. M., Ehmann, David E., Miller, Alita A.
Gepubliceerd in Antimicrob Agents Chemother (2015)

Myostatin and activin blockade by engineered follistatin results in hypertrophy and improves dystrophic pathology in mdx mouse more than myostatin blockade alone

door Iskenderian, Andrea, Liu, Nan, Deng, Qingwei, Huang, Yan, Shen, Chuan, Palmieri, Kathleen, Crooker, Robert, Lundberg, Dianna, Kastrapeli, Niksa, Pescatore, Brian, Romashko, Alla, Dumas, John, Comeau, Robert, Norton, Angela, Pan, Jing, Rong, Haojing, Derakhchan, Katayoun, Ehmann, David E.
Gepubliceerd in Skelet Muscle (2018)

Pharmacodynamic Profiling of a Siderophore-Conjugated Monocarbam in Pseudomonas aeruginosa: Assessing the Risk for Resistance and Attenuated Efficacy

door Kim, Aryun, Kutschke, Amy, Ehmann, David E., Patey, Sara A., Crandon, Jared L., Gorseth, Elise, Miller, Alita A., McLaughlin, Robert E., Blinn, Christina M., Chen, April, Nayar, Asha S., Dangel, Brian, Tsai, Andy S., Rooney, Michael T., Murphy-Benenato, Kerry E., Eakin, Ann E., Nicolau, David P.
Gepubliceerd in Antimicrob Agents Chemother (2015)

Translating slow-binding inhibition kinetics into cellular and in vivo effects

door Walkup, Grant K., You, Zhiping, Ross, Philip L., Allen, Eleanor K. H., Daryaee, Fereidoon, Hale, Michael R., O’Donnell, John, Ehmann, David E., Schuck, Virna J. A., Buurman, Ed T., Choy, Allison L., Hajec, Laurel, Murphy-Benenato, Kerry, Marone, Valerie, Patey, Sara A., Grosser, Lena A., Johnstone, Michele, Walker, Stephen G., Tonge, Peter J., Fisher, Stewart L.
Gepubliceerd in Nat Chem Biol (2015)