Molecular Mechanisms of Sulbactam Antibacterial Activity and Resistance Determinants in Acinetobacter baumannii

Sulbactam is a class A β-lactamase inhibitor with intrinsic whole-cell activity against certain bacterial species, including Acinetobacter baumannii. The clinical use of sulbactam for A. baumannii infections is of interest due to increasing multidrug resistance in this pathogen. However, the molecul...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Penwell, William F., Shapiro, Adam B., Giacobbe, Robert A., Gu, Rong-Fang, Gao, Ning, Thresher, Jason, McLaughlin, Robert E., Huband, Michael D., DeJonge, Boudewijn L. M., Ehmann, David E., Miller, Alita A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325763/
https://ncbi.nlm.nih.gov/pubmed/25561334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04808-14
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