Mitochondrial Proteomics of Antimony and Miltefosine Resistant Leishmania infantum

por Vincent, Isabel M., Racine, Gina, Légaré, Danielle, Ouellette, Marc
Publicado no Proteomes (2015)

Small Polar Hits against S. aureus: Screening, Initial Hit Optimization, and Metabolomic Studies

por Lim, Andrew S. T., Vincent, Isabel M., Barrett, Michael P., Gilbert, Ian H.
Publicado no ACS Omega (2019)

Untargeted metabolomic analysis of miltefosine action in Leishmania infantum reveals changes to the internal lipid metabolism()

por Vincent, Isabel M., Weidt, Stefan, Rivas, Luis, Burgess, Karl, Smith, Terry K., Ouellette, Marc
Publicado em 2013

Untargeted Metabolomics To Ascertain Antibiotic Modes of Action

por Vincent, Isabel M., Ehmann, David E., Mills, Scott D., Perros, Manos, Barrett, Michael P.
Publicado no Antimicrob Agents Chemother (2016)

Untargeted Metabolomics Reveals a Lack Of Synergy between Nifurtimox and Eflornithine against Trypanosoma brucei

por Vincent, Isabel M., Creek, Darren J., Burgess, Karl, Woods, Debra J., Burchmore, Richard J. S., Barrett, Michael P.
Publicado em 2012

Metabolomic profiling of macrophages determines the discrete metabolomic signature and metabolomic interactome triggered by polarising immune stimuli

por Rattigan, Kevin M., Pountain, Andrew W., Regnault, Clement, Achcar, Fiona, Vincent, Isabel M., Goodyear, Carl S., Barrett, Michael P.
Publicado no PLoS One (2018)

Metabolomics Identifies Multiple Candidate Biomarkers to Diagnose and Stage Human African Trypanosomiasis

por Vincent, Isabel M., Daly, Rónán, Courtioux, Bertrand, Cattanach, Amy M., Biéler, Sylvain, Ndung’u, Joseph M., Bisser, Sylvie, Barrett, Michael P.
Publicado no PLoS Negl Trop Dis (2016)

Different Mutations in a P-type ATPase Transporter in Leishmania Parasites are Associated with Cross-resistance to Two Leading Drugs by Distinct Mechanisms

por Fernandez-Prada, Christopher, Vincent, Isabel M., Brotherton, Marie-Christine, Roberts, Mathew, Roy, Gaétan, Rivas, Luis, Leprohon, Philippe, Smith, Terry K., Ouellette, Marc
Publicado no PLoS Negl Trop Dis (2016)

A Molecular Mechanism for Eflornithine Resistance in African Trypanosomes

por Vincent, Isabel M., Creek, Darren, Watson, David G., Kamleh, Mohammed A., Woods, Debra J., Wong, Pui Ee, Burchmore, Richard J. S., Barrett, Michael P.
Publicado em 2010

LM14 defined medium enables continuous growth of Trypanosoma cruzi

por De Paula Lima, Carla V, Batista, Michel, Kugeratski, Fernanda G, Vincent, Isabel M, Soares, Maurilio J, Probst, Christian M, Krieger, Marco A, Marchini, Fabricio K
Publicado em 2014

The trypanocidal benzoxaborole AN7973 inhibits trypanosome mRNA processing

por Begolo, Daniela, Vincent, Isabel M., Giordani, Federica, Pöhner, Ina, Witty, Michael J., Rowan, Timothy G., Bengaly, Zakaria, Gillingwater, Kirsten, Freund, Yvonne, Wade, Rebecca C., Barrett, Michael P., Clayton, Christine
Publicado no PLoS Pathog (2018)

The threonine degradation pathway of the Trypanosoma brucei procyclic form: the main carbon source for lipid biosynthesis is under metabolic control

por Millerioux, Yoann, Ebikeme, Charles, Biran, Marc, Morand, Pauline, Bouyssou, Guillaume, Vincent, Isabel M, Mazet, Muriel, Riviere, Loïc, Franconi, Jean-Michel, Burchmore, Richard J S, Moreau, Patrick, Barrett, Michael P, Bringaud, Frédéric
Publicado em 2013

Benzoxaborole treatment perturbs S-adenosyl-L-methionine metabolism in Trypanosoma brucei

por Steketee, Pieter C., Vincent, Isabel M., Achcar, Fiona, Giordani, Federica, Kim, Dong-Hyun, Creek, Darren J., Freund, Yvonne, Jacobs, Robert, Rattigan, Kevin, Horn, David, Field, Mark C., MacLeod, Annette, Barrett, Michael P.
Publicado no PLoS Negl Trop Dis (2018)

Sterol 14α-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana

por Mwenechanya, Roy, Kovářová, Julie, Dickens, Nicholas J., Mudaliar, Manikhandan, Herzyk, Pawel, Vincent, Isabel M., Weidt, Stefan K., Burgess, Karl E., Burchmore, Richard J. S., Pountain, Andrew W., Smith, Terry K., Creek, Darren J., Kim, Dong-Hyun, Lepesheva, Galina I., Barrett, Michael P.
Publicado no PLoS Negl Trop Dis (2017)

Host-parasite co-metabolic activation of antitrypanosomal aminomethyl-benzoxaboroles

por Zhang, Ning, Zoltner, Martin, Leung, Ka-Fai, Scullion, Paul, Hutchinson, Sebastian, del Pino, Ricardo C., Vincent, Isabel M., Zhang, Yong-Kang, Freund, Yvonne R., Alley, Michael R. K., Jacobs, Robert T., Read, Kevin D., Barrett, Michael P., Horn, David, Field, Mark C.
Publicado no PLoS Pathog (2018)

Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs

por Giordani, Federica, Paape, Daniel, Vincent, Isabel M., Pountain, Andrew W., Fernández-Cortés, Fernando, Rico, Eva, Zhang, Ning, Morrison, Liam J., Freund, Yvonne, Witty, Michael J., Peter, Rosemary, Edwards, Darren Y., Wilkes, Jonathan M., van der Hooft, Justin J. J., Regnault, Clément, Read, Kevin D., Horn, David, Field, Mark C., Barrett, Michael P.
Publicado no PLoS Pathog (2020)

TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei

por Shameer, Sanu, Logan-Klumpler, Flora J., Vinson, Florence, Cottret, Ludovic, Merlet, Benjamin, Achcar, Fiona, Boshart, Michael, Berriman, Matthew, Breitling, Rainer, Bringaud, Frédéric, Bütikofer, Peter, Cattanach, Amy M., Bannerman-Chukualim, Bridget, Creek, Darren J., Crouch, Kathryn, de Koning, Harry P., Denise, Hubert, Ebikeme, Charles, Fairlamb, Alan H., Ferguson, Michael A. J., Ginger, Michael L., Hertz-Fowler, Christiane, Kerkhoven, Eduard J., Mäser, Pascal, Michels, Paul A. M., Nayak, Archana, Nes, David W., Nolan, Derek P., Olsen, Christian, Silva-Franco, Fatima, Smith, Terry K., Taylor, Martin C., Tielens, Aloysius G. M., Urbaniak, Michael D., van Hellemond, Jaap J., Vincent, Isabel M., Wilkinson, Shane R., Wyllie, Susan, Opperdoes, Fred R., Barrett, Michael P., Jourdan, Fabien
Publicado no Nucleic Acids Res (2014)