Untargeted Metabolomics To Ascertain Antibiotic Modes of Action

Deciphering the mode of action (MOA) of new antibiotics discovered through phenotypic screening is of increasing importance. Metabolomics offers a potentially rapid and cost-effective means of identifying modes of action of drugs whose effects are mediated through changes in metabolism. Metabolomics...

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Udgivet i:Antimicrob Agents Chemother
Main Authors: Vincent, Isabel M., Ehmann, David E., Mills, Scott D., Perros, Manos, Barrett, Michael P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Mechanisms of Action: Physiological Effects
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808186/
https://ncbi.nlm.nih.gov/pubmed/26833150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02109-15
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