Investigations of the Mode of Action and Resistance Development of Cadazolid, a New Antibiotic for Treatment of Clostridium difficile Infections

Cadazolid is a new oxazolidinone-type antibiotic currently in clinical development for the treatment of Clostridium difficile-associated diarrhea. Here, we report investigations on the mode of action and the propensity for spontaneous resistance development in C. difficile strains. Macromolecular la...

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Bibliografische gegevens
Hoofdauteurs: Locher, Hans H., Caspers, Patrick, Bruyère, Thierry, Schroeder, Susanne, Pfaff, Philippe, Knezevic, Andreja, Keck, Wolfgang, Ritz, Daniel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2014
Onderwerpen:
Mechanisms of Action: Physiological Effects
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910891/
https://ncbi.nlm.nih.gov/pubmed/24277035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01831-13
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