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Different Resistance Mechanisms for Cadazolid and Linezolid in Clostridium difficile Found by Whole-Genome Sequencing Analysis

Cadazolid (CDZ) is a new antibiotic currently in clinical development for the treatment of Clostridium difficile infections. CDZ interferes with the bacterial protein synthesis machinery. The aim of the present study was to identify resistance mechanisms for CDZ and compare the results to those obta...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Caspers, Patrick, Locher, Hans H., Pfaff, Philippe, Diggelmann, Sarah, Rueedi, Georg, Bur, Daniel, Ritz, Daniel
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527658/
https://ncbi.nlm.nih.gov/pubmed/28584149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00384-17
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