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Different Resistance Mechanisms for Cadazolid and Linezolid in Clostridium difficile Found by Whole-Genome Sequencing Analysis

Cadazolid (CDZ) is a new antibiotic currently in clinical development for the treatment of Clostridium difficile infections. CDZ interferes with the bacterial protein synthesis machinery. The aim of the present study was to identify resistance mechanisms for CDZ and compare the results to those obta...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Caspers, Patrick, Locher, Hans H., Pfaff, Philippe, Diggelmann, Sarah, Rueedi, Georg, Bur, Daniel, Ritz, Daniel
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527658/
https://ncbi.nlm.nih.gov/pubmed/28584149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00384-17
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