Mode of Action and Bactericidal Properties of Surotomycin against Growing and Nongrowing Clostridium difficile

Surotomycin (CB-183,315), a cyclic lipopeptide, is in phase 3 clinical development for the treatment of Clostridium difficile infection. We report here the further characterization of the in vitro mode of action of surotomycin, including its activity against growing and nongrowing C. difficile. This...

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Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Main Authors: Alam, Mohammed Zahidul, Wu, Xiaoqian, Mascio, Carmela, Chesnel, Laurent, Hurdle, Julian G.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2015
Teme:
Mechanisms of Action: Physiological Effects
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538476/
https://ncbi.nlm.nih.gov/pubmed/26055381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01087-15
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