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Mode of Action and Bactericidal Properties of Surotomycin against Growing and Nongrowing Clostridium difficile

Surotomycin (CB-183,315), a cyclic lipopeptide, is in phase 3 clinical development for the treatment of Clostridium difficile infection. We report here the further characterization of the in vitro mode of action of surotomycin, including its activity against growing and nongrowing C. difficile. This...

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Alam, Mohammed Zahidul, Wu, Xiaoqian, Mascio, Carmela, Chesnel, Laurent, Hurdle, Julian G.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538476/
https://ncbi.nlm.nih.gov/pubmed/26055381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01087-15
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