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Mode of Action and Bactericidal Properties of Surotomycin against Growing and Nongrowing Clostridium difficile

Surotomycin (CB-183,315), a cyclic lipopeptide, is in phase 3 clinical development for the treatment of Clostridium difficile infection. We report here the further characterization of the in vitro mode of action of surotomycin, including its activity against growing and nongrowing C. difficile. This...

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書目詳細資料
發表在:Antimicrob Agents Chemother
Main Authors: Alam, Mohammed Zahidul, Wu, Xiaoqian, Mascio, Carmela, Chesnel, Laurent, Hurdle, Julian G.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538476/
https://ncbi.nlm.nih.gov/pubmed/26055381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01087-15
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