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Mode of Action and Bactericidal Properties of Surotomycin against Growing and Nongrowing Clostridium difficile

Surotomycin (CB-183,315), a cyclic lipopeptide, is in phase 3 clinical development for the treatment of Clostridium difficile infection. We report here the further characterization of the in vitro mode of action of surotomycin, including its activity against growing and nongrowing C. difficile. This...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Main Authors: Alam, Mohammed Zahidul, Wu, Xiaoqian, Mascio, Carmela, Chesnel, Laurent, Hurdle, Julian G.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538476/
https://ncbi.nlm.nih.gov/pubmed/26055381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01087-15
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